基于意识指数的麻醉深度监测临床研究进展

Clinical research progress on anesthesia depth monitoring based on index of consciousness

在全凭静脉麻醉管理过程中,对于麻醉深度尤其是对全身麻醉患者术中伤害性刺激强度的准确判断一直是一大难题。近年来,随着人们对脑电研究的深入,一种新型的通过分析脑电来监测麻醉深度的设备——基于意识指数(index ofconsciousness, IoC)的麻醉深度监测设备逐渐在临床中应用。文章通过介绍脑电监测技术的基本原理,简要介绍了各种基于脑电的麻醉监测参数[如BIS、麻醉趋势指数(Narcotrend index, NI)、听觉诱发电位(auditory evoked potential, AEP)及IoC等],比较了IoC监测设备相较于其他麻醉深度监测设备的优势,详细描述了各种研究中IoC监测设备的应用场景、优势及其结论,并分析了影响脑电监测准确性的因素。

During the process of total intravenous anesthesia management, it is always difficult to accurately judge the depth ofanesthesia, especially the intensity of intraoperative noxious stimulation in patients under general anesthesia. In recent years, with thedeepening of electroencephalogram (EEG) research, a new type of equipment as adopted to monitor the depth of anesthesia by analyzingEEG. The depth of anesthesia monitoring equipment based on the index of consciousness (IoC) is gradually applied in clinical practice.By introducing the basic principle of EEG monitoring technology, this paper briefly introduces various anesthesia monitoring parameters based on EEG [such as bispectral index (BIS), Narcotrend index (NI), auditory evoked potential (AEP), IoC, and so on], comparesthe advantages of IoC monitoring equipment compared with other anesthesia depth monitoring equipment, describes in detail the application scenarios, advantages and conclusions of IoC monitoring equipment in various studies, and analyzes the factors affecting the accuracy of EEG monitoring.