中药灌肠联合脐灸辨证治疗慢性盆腔炎的临床效果与安全性评价

Clinical effect and safety evaluation of traditional Chinese medicine enema combined with umbilical moxibustion in syndrome differentiation treatment of chronic pelvic inflammatory disease

目的探讨中药灌肠联合脐灸辨证治疗慢性盆腔炎的效果与安全性评价。方法选取2019年1月至2020年12月我院门诊的寒湿凝滞型慢性盆腔炎患者80例,采用随机数字法分为观察组与对照组,每组各40例,观察组患者给予中药灌肠联合脐灸辨证治疗,对照组患者给予中药灌肠治疗,比较两组患者的临床治疗总有效率及治疗前后血清炎性水平及B超指标盆腔积液深度和盆腔包块直径。结果观察组患者临床治疗总有效率显著高于对照组,差异有统计学意义(P<0.05);两组患者的血清CRP、TNF-α水平及盆腔积液深度和盆腔包块直径治疗前比较,差异均无统计学意义(P>0.05),与对照组治疗后比较,观察组患者的CRP、TNF-α水平和盆腔积液深度和盆腔包块直径均显著降低(P<0.05);与治疗前比较,两组治疗后TNF-α、CRP水平和盆腔积液深度和盆腔包块直径均显著降低,差异有统计学意义(P<0.05);两组治疗期间均未见明显不良反应。结论中药灌肠联合脐灸辨证治疗寒湿凝滞型慢性盆腔炎的临床效果较好,能够显著降低患者炎症水平及疼痛感,安全性较好。

Objective To explore the efficacy and safety of traditional Chinese medicine enema combined with umbilical moxibustion in the syndrome differentiation treatment of chronic pelvic inflammatory disease.Methods Eighty patients with chronic pelvic inflammatory disease of the cold-damp stagnation type in our hospital from January 2019 to December 2020 were selected and divided into the observation group and the control group by the random number method,with 40 cases in each group.Patients in the observation group were given traditional Chinese medicine enema combined with umbilical moxibustion syndrome differentiation,and patients in the control group were given traditional Chinese medicine enema treatment.The total clinical effective rates,serum inflammatory levels before and after treatment,and the B ultrasonic indicators of pelvic effusion depth and pelvic mass diameter of the two groups were compared.Results The total effective rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,no significant differences were observed in the serum CRP levels,TNF-αlevels,pelvic effusion depth and pelvic mass diameters between the 2 groups(P>0.05).Compared with the control group after treatment,the levels of CRP and TNF-α,the depth of pelvic effusion and the diameter of pelvic mass in the observation group were significantly decreased(P<0.05).Compared with before treatment,the levels of TNF-αand CRP,the depth of pelvic effusion and the diameter of pelvic mass of two groups were significantly decreased after treatment,with statistically significant differences(P<0.05).No obvious adverse reactions during the treatment were observed in two groups.Conclusion Traditional Chinese medicine enema combined with umbilical moxibustion in the syndrome differentiation treatment of the cold-damp stagnation type of chronic pelvic inflammatory disease has good clinical effect,and can significantly reduce the level of inflammation and pain in patients,with good safety.