急性纤维素性机化性肺炎影像学研究进展

Research progress on imaging study of acute fibrinous and organizing pneumonia

急性纤维素性机化性肺炎(acute fibrinous and organizing pneumonia,AFOP)具有急性、亚急性临床表现,肺泡腔内的纤维蛋白球为其组织病理学的特征性改变,是特发性间质性肺炎(idiopathic interstitial pneumonia,IIP)的一种罕见的病理类型。影像学表现以双肺斑片状、片状及团块样实变多见,主要分布在支气管血管束周围或胸膜下,常伴有空气支气管征。其次为磨玻璃阴影、结节、网状或线样阴影。由于临床及影像学表现多不典型,确诊应结合临床、影像及病理学检查,在排除其他诊断后可以考虑AFOP。

Acute fibrinous and organizing pneumonia(AFOP)has acute and subacute clinical presentation.The fibrin ball in the alveolar cavity is a characteristic histopathological change.AFOP is a rare case of idiopathic interstitial pneumonia.The imaging findings were patchy/flaky or mass-like airspace consolidation,which were mainly distributed around the peribronchial or under the pleura,and accompanied by air bronchograms.The second was ground-glass opacity,nodules,reticular or linear opacities.Because the clinical and imaging presentation are not typical,the diagnosis should be combined with clinical,imaging and pathological examination,and AFOP can be considered after excluding other diagnoses.