体素内不相干运动技术在骨肿瘤诊断的研究进展

Application progresses of intravoxel incoherent motion technique in Bone Tumors

DWI可以无创性检测活体水分子扩散运动。近年来,在常规DWI基础上开发的体素内不相干运动(intravoxel incoherent motion,IVIM)扩散加权成像,是近几年发展起来的无创评价活体组织内分子扩散及灌注的MRI新技术,并且已经广泛用于头颈部、肝脏、乳腺、前列腺等,而在骨肿瘤的应用相对较少。现主要对IVIM的原理及其在骨肿瘤中的应用进展作一综述。

Diffusion weighted MR imaging(DW-MRI)provides information about molecular diffusion of water noninvasively.Intravoxel incoherent motion(IVIM)is an new technique based on traditional DWI,which defines the ability to separate blood perfusion from true diffusion effects via a proper choice of the number and distribution of diffusion weightings,or b-values.And IVIM has been widely applied in the head and neck,liver,breast,prostate and so on,but rarely applied in bone tumor.This article aims to review the principle of IVIM and its application in bone tumors.