血尿酸、血肌酐水平对糖尿病肾病患者预后判断的价值

The prognostic value of serum uric acid and creatinine levels in patients with diabetic nephropathy

目的:研究血尿酸(UA)、血肌酐(Cr)指标应用于判断糖尿病肾病患者预后的价值与意义。方法:2019年1月-2020年12月收治糖尿病肾病患者120例,作为观察组;另选取同一时期行体检的健康者120例,作为对照组。所有受试者均接受血液检查;比较两组UA、Cr及血脂水平。结果:观察组UA、Cr、TC、TG、LDL-C水平均显著高于对照组,HDL-C水平显著低于对照组,差异均有统计学意义(P<0.05)。观察组治疗后UA、Cr水平显著降低,且此两项指标与糖尿病肾病预后情况呈正相关,是影响预后的重要因素。结论:糖尿病肾病患者UA、Cr及血脂水平可作为评估疾病治疗效果及预后情况的重要指标,可为临床指导疾病治疗提供客观、准确的理论依据。

Objective:To study the prognostic value and significance of serum uric acid(UA)and serum creatinine(Cr)in patients with diabetic B nephropathy.Methods:From January 2019 to December 2020,120 patients with diabetic nephropathy were treated as observation group.Another 120 healthy subjects who underwent physical examination at the same period were selected as the control group.All subjects underwent blood tests.UA,Cr and lipid levels were compared between the two groups.Results:The levels of UA,Cr,TC,TG and LDL-C in the observation group were significantly higher than the control group,while HDL-C level was significantly lower than the control group,the differences were statistically significant(P<0.05).The levels of UA and Cr in the observation group were significantly reduced after treatment,and these two indicators were positively correlated with the prognosis of diabetic nephropathy,which were important factors affecting the prognosis.Conclusion:UA,Cr and lipid levels in diabetic nephropathy patients can be used as important indicators to evaluate the therapeutic effect and prognosis of the disease,and provide objective and accurate theoretical basis for clinical guidance of the treatment of the disease.