哮喘平糖浆早期治疗婴儿毛细支气管炎的近期效果及远期预后

The Short-term Effect and Long-term Prognosis of Asthma Ping Syrup in Early Treatment of Infant Bronchiolitis

目的:探讨哮喘平糖浆(院内制剂)早期治疗婴儿毛细支气管炎的近期效果及远期预后。方法:选取襄阳市中医医院2018年1月-2020年1月诊断为毛细支气管炎住院治疗且符合观察要求的婴儿112例,以随机数字表法分为治疗组60例和对照组52例,两组均给予常规综合治疗,治疗组在以上治疗的基础上,给予哮喘平糖浆治疗7 d。观察比较两组喘憋、咳嗽、肺部湿啰音消失时间及住院时间,不良反应,并于治疗后12个月评价比较远期预后。结果:治疗组喘憋、咳嗽、肺部湿啰音消失时间分别为(4.88±1.79)、(6.46±1.65)、(5.80±1.38)d,住院时间为(6.88±2.42)d,对照组喘憋、咳嗽、肺部体征消失时间分别为(6.10±1.91)、(7.55±1.94)、(6.80±1.92)d,住院时间为(7.85±2.14)d,治疗组喘憋、咳嗽、肺部湿啰音消失时间、住院时间明显优于对照组(P<0.05);治疗组治愈61.67%(37/60),显效30.0%(18/60),有效6.67%(4/60),无效1.67%(1/60),对照组治愈38.46%(20/52),显效26.92%(14/52),有效19.23%(10/52),无效15.38%(8/52),两组总有效率比较差异有统计学意义(P<0.05);治疗组远期预后与对照组比较差异无统计学意义(P>0.05)。结论:哮喘平糖浆早期治疗婴儿毛细支气管炎的效果确切,可用于婴儿期毛细支气管炎早期治疗,远期预后无优势。

Objective:To explore the short-term effect and long-term prognosis of Asthma Ping Syrup(hospital preparation)in early treatment of infant bronchiolitis.Method:A total of 112 cases admitted into Xiangyang City Chinese Medicine Hospital for treatment from January 2018 to January 2020 diagnosed with bronchiolitis and meet the requirements of the observation were selected.With random number table method,they were divided into the treatment group 60 cases and the control group 52 cases.Both groups were given conventional comprehensive treatment,the treatment group was given Asthma Ping Syrup treatment for 7 d on the basis of the above treatment.The two groups were observed and compared in the disappearance time of wheezing,cough,lung wet rales,hospital stay and adverse reactions,and the two groups were evaluated and compared in the long-term prognosis 12 months after treatment.Result:In the treatment group,the disappearance time of wheezes,cough and lung wet rales were(4.88±1.79),(6.46±1.65),(5.80±1.38)d,and the hospital stay was(6.88±2.42)d,respectively.The disappearance time of wheezes,cough and lung wet rales in the control group were(6.10±1.91),(7.55±1.94),(6.80±1.92)d,and the hospital stay was(7.85±2.14)d respectively.The disappearance time of wheezes cough and lung wet rales and the hospital stay in the treatment group were significantly better than those in the control group(P<0.05).The treatment group cured 61.67%(37/60),significant effect 30.0%(18/60),effective 6.67%(4/60),ineffective 1.67%(1/60),the control group cured 38.46%(20/52),significant effect 26.92%(14/52),effective 19.23%(10/52),ineffective 15.38%(8/52).There was significant difference in total effective rate between the two groups(P<0.05).There was no significant difference in long-term prognosis between the treatment group and the control group(P>0.05).Conclusion:Asthma Ping Syrup has a definite effect on the early treatment of infant bronchiolitis,and can be used for the early treatment of infant bronchiolitis,with no advantage in the long-term prognosis.