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细胞外囊泡及其相关的蛋白质修饰与心血管疾病关系的研究进展

Research progress on the relationship between extracellular vesicles and related protein modifications with cardiovascular diseases
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摘要 细胞外囊泡(EV)是细胞分泌的具有介导细胞间信息交流功能的囊泡状物质,与心血管疾病的发生发展密切相关。蛋白质修饰对EV的产生、性质和生物学效应有重要作用。近年来,心血管疾病中EV的改变、作用以及相关的蛋白质修饰已经成为重要的研究方向。该文对EV及其相关的蛋白质修饰与心血管疾病关系的研究进展、局限性及发展方向进行了综述。
作者 刘晓军 欧志君 区景松 Liu Xiaojun;Ou Zhijun;Ou Jingsong(Division of Cardiac Surgery,First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China;National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases,National Health Commission Key Laboratory of Assisted Circulation(Sun Yat-sen University),Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular Diseases,Guangdong Provincial Key Laboratory of Brain Function and Disease,Guangzhou 510080,China;Division of Hypertension and Vascular Diseases,First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China)
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2021年第11期1163-1168,共6页 Chinese Journal of Cardiology
基金 国家自然科学基金(81670392,81770241,81830013,81970363) 教育部长江学者资助计划(T2014181) 广东省自然科学基金(2015A030312009) 广东省基础与应用基础研究基金(2019B1515120092)。
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