留置导尿患者导尿管表面生物膜形成的危险因素分析

Analysis of risk factors of biofilm formation on catheter surface in patients with indwelling urinary catheter

目的了解留置导尿患者导尿管表面生物膜形成的危险因素,为生物膜控制提供参考。方法采用扫描电镜观察法和统计分析法,对某医院住院留置导尿患者使用后导尿管进行观察,分析影响因素。结果经对117例留置导尿患者使用后的导尿管观察发现,使用时间较长的乳胶导尿管通过扫描电镜可观察到形成的生物膜。多因素分析表明,乳胶导尿管、留置导尿时间过长、抗菌药物使用种类≥3种等因素是导尿管表面生物膜形成的独立危险因素。结论使用时间过长的乳胶导尿管容易形成生物膜,时间因素和使用多种抗菌药物等因素可助长生物膜的形成。

Objective To understand the risk factors of biofilm formation on catheter surface in in patients with indwelling urinary catheter,and to provide references for biofilm control.Methods The scanning electron microscope observation method and statistical analysis method were used to observe the catheter used by inpatients with indwelling urinary catheter in a hospital,and the influencing factors were analyzed.Results The catheters of 117 patients with indwelling urinary catheters were observed,and the formation of biofilm could be observed by scanning electron microscopy in latex urinary catheters that had been used for a long time.Multivariate analysis showed that latex urinary catheter,long indwelling catheterization time,and use of antibiotics≥3 were independent risk factors for the formation of biofilm on the surface of the catheter.Conclusion It is easy to form biofilm in latex urinary catheters that have been used for a long time.Time factor and use of a variety of antibacterial drugs can promote the formation of biofilms.