摘要
[目的]观察配戴硬性高透氧性角膜接触镜(RGP)矫正不规则散光患者的临床疗效及对泪膜稳定性和泪液分泌的影响。[方法]收集2017年1月至2018年4月36例(38眼)不规则散光患者,测量框架眼镜、RGP眼镜的矫正视力;检测RGP戴镜前及戴镜后1 d、1 mon、6 mon、12 mon的泪膜破裂时间;检测基础泪液分泌试验、泪河高度、干眼症状评分及角膜染色情况。[结果]框架眼镜矫正视力0.321±0.154,RGP矫正视力0.658±0.233,二者比较P<0.05,差异有统计学意义,RGP矫正不规则散光优于框架眼镜。泪膜破裂时间、基础泪液分泌、泪河高度在配戴RGP超过6 mon后,与戴镜前比较,P<0.05差异有统计学意义,且随着戴镜时间的延长三者均逐渐减少。干眼症状在戴镜大于6 mon后逐渐明显,与戴镜前比较差异有统计学意义。RGP戴镜后出现了Ⅰ级角膜染色,在戴镜1 d后角膜染色率最高,随时间延长渐稳定。[结论]RGP可以有效矫正不规则散光,但配戴时间超过6 mon可至泪膜不稳定、泪液分泌减少且干眼症状加重。
[Objective]To observe the clinical effect of RGP on irregular astigmatism and its influence on tear film stability and tear secretion.[Methods]36 cases(38 eyes) with irregular astigmatism were collected from January 2017 to April 2018.The corrected visual acuity of frame glasses and RGP glasses were measured,break-up time(BUT),Schirmer I test(SIt),tear river height(TMH),dry eye symptom score and corneal staining(FL) before and 1 day,1 month,6 months,12 months after wearing RGP.[Results ]The corrected visual acuity of frame glasses was 0.321±0.154,and that of RGP was 0.658±0.233.The difference was statistically significant(P<0.05).RGP was superior to frame glasses in correcting irregular astigmatism.The time of tear film rupture,Basal Tear Secretion and height of tear river after wearing RGP for more than half a year were significantly different from those before wearing RGP,P<0.05.The symptoms of dry eye became obvious after wearing glasses for more than half a year,and the difference was statistically significant.RGP showed grade Ⅰ corneal staining after wearing glasses,the highest staining rate was 1 day after wearing glasses,and it became stable with time.[Conclusion] RGP can correct irregular astigmatism effectively,but more than half a year may result unstable tear film,decreased tear secretion and increased dry eye symptoms.
作者
梁圆圆
柴珺
于亚东
杨彬
胡馨
赵博
LIANG Yuanyuan;CHAI Jun;YU Yadong;YANG Bin;HU Xin;ZHAO Bo(Department of Ophthalmology Huaihe Hospital of Henan University,Kaifeng 475000 China)
出处
《河南大学学报(医学版)》
CAS
2021年第5期341-344,共4页
Journal of Henan University:Medical Science
关键词
泪膜
泪液分泌
干眼
不规则散光
硬性高透氧性角膜接触镜
tear film
tear secretion
dry eye
irregular astigmatism
rigid oxygen permeable contact lenses