观察联合治疗方案对原发性失眠患者睡眠质量、抑郁情绪的改善效果

To Observe the Effect of Combined Treatment on Sleep Quality and Depression in Patients with Primary Insomnia

目的:分析联合治疗方案对原发性失眠患者睡眠质量、抑郁情绪及睡眠结构指标的效果。方法:选取2017年5月至2020年1月枣庄市精神卫生中心收治的原发性失眠患者70例作为研究对象,按照随机数字表法分为观察组和对照组,每组35例。对照组采用唑吡坦联合经颅磁假性刺激进行治疗,观察组采用唑吡坦联合经颅磁真性刺激进行治疗,采用简单自测抑郁量表(PHQ-9)评估患者抑郁情绪,并对2组患者的睡眠结构指标进行评估。结果:治疗后,观察组各项指标优于对照组,2组比较差异有统计学意义(P<0.05)。结论:唑吡坦联合经颅磁真性刺激治疗对原发性失眠患者治疗效果较好,值得临床推广使用。

Objective:To analyze the effects of combined therapy on sleep quality,depressive mood and sleep structure in patients with primary insomnia.Methods:A total of 70 patients with primary insomnia admitted to Zaozhuang Mental Health Center from May 2017 to January 2020 were selected as research objects,and were divided into observation group and control group according to random number table method,with 35 patients in each group.The control group was treated with Zolpidem combined with TMS sham stimulation,and the observation group was treated with Zolpidem combined with TMS true stimulation.The depressive mood of the patients was assessed with the simple self-measuring Depression Scale(PHQ-9),and the sleep outcome indexes of the patients between two groups were evaluated.Results:After treatment,the indicators of the observation group were better than those of the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion:Zolpidem combined with transcranial magnetic stimulation(TMS)has a good therapeutic effect on patients with primary insomnia,which is worthy of clinical application.