新生儿输血相关性坏死性小肠结肠炎1例

A case of transfusion-associated necrotizing enterocolitis in neonates

1例男性新生儿,胎龄28周2 d,出生体重1120 g,早产后20 min入住四川大学华西第二医院新生儿重症监护室。住院30 d时因贫血(血红蛋白为81 g/L)予输血治疗,输血过程中继续喂养。输血结束8 h后,患儿逐渐出现腹胀、张力增高、肠鸣音减弱、解暗红色大便,反应差、呼吸暂停等表现,临床诊断为坏死性小肠结肠炎。腹部X线显示腹腔肠管扩张明显、充气,立即予禁食、胃肠减压、灌肠、抗感染治疗等处理,住院40 d后痊愈出院。

A male infant,whose weight was 1120 g at 28+2 weeks of gestational age,was admitted to Neonatal Intensive Care Unit of West China Second Hospital of Sichuan University at 20 min after preterm birth.Blood transfusion was performed for anemia(hemoglobin 81 g/L)on day 30 of hospitalization,and feeding was continued during the transfusion.Eight hours after blood transfusion,the patient's manifestations included abdominal distension and stiff to palpation,bowel sound weakening,currant jelly stool,poor responsiveness,and apnea.The clinical diagnosis was necrotizing enterocolitis.Abdominal X-ray showed that the abdominal bowel was significantly dilated and inflated.The patient was immediately treated with fasting,gastrointestinal decompression,enema,and anti-infection treatment.After 40 days in hospital,the patient recovered and was discharged.