产后逐瘀胶囊联合常规措施治疗产后腹痛气滞血瘀证疗效研究

Study on Curative Effect of Postpartum Zhuyu Capsules Combined with Routine Measures for Postpartum Abdominal Pain with Qi Stagnation and Blood Stasis Syndrome

目的:观察在产后常规干预措施基础上加用产后逐瘀胶囊治疗产后腹痛气滞血瘀证的临床疗效。方法:纳入66例产后腹痛气滞血瘀证患者,按随机数字表法分为2组各33例。2组均给予产后常规干预措施,观察组加予产后逐瘀胶囊,2组疗程均为5 d。比较2组治疗前、治疗5 d的疼痛程度[疼痛评级指数(PRI)、视觉模拟评分法(VAS)、现在疼痛状况(PPI)]、疼痛分级情况、血液流变学指标(全血高切黏度、全血低切黏度、纤维蛋白原)。结果:治疗后,2组PRI、VAS、PPI评分均较治疗前降低(P<0.01),观察组3项评分均低于对照组(P<0.01)。观察组0级疼痛的患者比例高于对照组(P<0.05)。2组全血高切黏度、全血低切黏度、纤维蛋白原水平均较治疗前降低(P<0.01),观察组全血高切黏度、全血低切黏度、纤维蛋白原水平均低于对照组(P<0.01)。结论:在产后常规干预措施基础上加用产后逐瘀胶囊能有效减轻产后腹痛气滞血瘀证患者的腹痛程度,且可改善血液流变学。

Objective:To observe the clinical effect of the additional application of postpartum Zhuyu capsules based on routine postpartum intervention measures for postpartum abdominal pain with qi stagnation and blood stasis syndrome.Methods:A total of 66 cases of patients with postpartum abdominal pain were included and divided into two groups according to the random number table method,33 cases in each group.Both groups were given routine postpartum intervention measures,and the observation group was additionally given postpartum Zhuyu capsules.Both groups were treated for five days.Before treatment and after five-day treatment respectively,the pain degree including Pain Rating Index(PRI),Visual Analogue Scale(VAS)and Present Pain Intensity(PPI),pain gradings,and hemorheology indexes including whole blood high shear viscosity,whole blood low shear viscosity and fibrinogen in the two groups were compared.Results:After treatment,the scores of PRI,VAS and PPI in the two groups were decreased when compared with those before treatment(P<0.01),and the above three scores in the observation group were lower than those in the control group(P<0.01).The proportion of patients with Grade 0 pain in the observation group was higher than that in the control group(P<0.05).The levels of whole blood high shear viscosity,whole blood low shear viscosity and fibrinogen in the two groups were decreased when compared with those before treatment(P<0.01),and the levels in the observation group were lower than those in the control group(P<0.01).Conclusion:Based on routine postpartum intervention measures,the additional application of postpartum Zhuyu capsules for patients with postpartum abdominal pain with qi stagnation and blood stasis syndrome can effectively reduce their pain degree and improve their hemorheology.