丹斛通痹汤内服与穴位贴敷联合常规疗法治疗原发性高血压临床研究

Clinical Study on Oral Administration of Danhu Tongbi Tang and Point Application Combined with Routine Therapy for Primary Hypertension

目的:观察丹斛通痹汤内服与穴位贴敷联合常规疗法治疗原发性高血压的临床疗效。方法:将112例气阴两虚兼心脉瘀阻型原发性高血压患者按随机数字表法分为对照组和观察组各56例。2组均根据病情采用相应的降压药治疗,并给予常规护理措施进行干预,观察组加予丹斛通痹汤内服联合穴位贴敷治疗。2组均连续治疗4周。观察治疗前、治疗4周后,2组患者血压、血压变异系数及气阴两虚兼心脉瘀阻证主症的变化情况。比较2组的临床疗效。结果:治疗4周后,观察组临床疗效总有效率高于对照组(P<0.05)。2组收缩压、舒张压均较治疗前下降(P<0.01),观察组收缩压、舒张压均低于对照组(P<0.01)。2组24 h舒张压变异系数、24 h收缩压变异系数均较治疗前下降(P<0.01),观察组24 h舒张压变异系数、24 h收缩压变异系数均低于对照组(P<0.01)。2组眩晕时作、短气乏力、口干心烦、头痛如刺有定处评分均较治疗前降低(P<0.01),观察组4项症状评分均低于对照组(P<0.01)。结论:在常规疗法基础上加用丹斛通痹汤联合穴位贴敷治疗气阴亏虚型兼心脉瘀阻型原发性高血压疗效明显,可有效缓解症状,发挥良好的降压效果。

Objective:To observe the clinical effect of oral administration of Danhu Tongbi tang and point application combined with routine therapy for primary hypertension.Methods:A total of 112 cases of patients with primary hypertension of deficiency of both qi and yin combined with heart vessel stasis obstruction type were divided into the control group and the observation group according to the random number table method,56 cases in each group.Both groups were treated with corresponding antihypertensive drug based on their disease condition,and intervened with routine nursing measures,and the observation group was additionally treated with oral administration of Danhu Tongbi tang combined with point application.Both groups were treated for four weeks.Before treatment and after four-week treatment,the changes in blood pressure,blood pressure variability and main symptoms of deficiency of both qi and yin combined with heart vessel stasis obstruction syndrome in the two groups were observed.The clinical effect in the two groups was compared.Results:After four-week treatment,the total effective rate of clinical effect in the observation group was higher than that in the control group(P<0.05).The systolic pressure and diastolic pressure in the two groups were decreased when compared with those before treatment(P<0.01),and the systolic pressure and diastolic pressure in the observation group were lower than those in the control group(P<0.01).The 24-hour diastolic blood pressure coefficient of variability and 24-hour systolic blood pressure coefficient of variability in the two groups were decreased when compared with those before treatment(P<0.01),and the 24-hour diastolic blood pressure coefficient of variability and 24-hour systolic blood pressure coefficient of variability in the observation group were lower than those in the control group(P<0.01).The scores of vertigo,shortness of breath and fatigue,dry mouth and vexation and headache with pricking at certain points in the two groups were decreased when compared with those before treatment(P<0.01),and the above four symptom scores in the observation group were lower than those in the control group(P<0.01).Conclusion:Based on routine therapy,the application of Danhu Tongbi tang combined with point application for primary hypertension of deficiency of both qi and yin combined with heart vessel stasis obstruction type has significant curative effect,and can effectively relieve symptoms and exert good antihypertensive effect.