PKEP与HoLEP治疗老年良性前列腺增生的短期临床疗效比较

Comparison of Short-term Clinical Efficacy of PKEP and HoLEP in the Treatment of Senile Benign Prostatic Hyperplasia

【目的】比较经尿道等离子前列腺剜除术(PKEP)和经尿道钬激光前列腺剜除术(HoLEP)治疗老年良性前列腺增生(BPH)的短期临床疗效。【方法】选取2017年3月至2019年5月本院收治的68例BPH患者为研究对象,按照随机数表法将其分为HoLEP组、PKEP组,各34例。PKEP组患者行PKEP术治疗,HoLEP组患者行HoLEP术治疗,比较两组患者手术情况、临床疗效及不良反应发生率。【结果】HoLEP组患者术中出血量小于PKEP组,手术时间、尿管留置时间、住院时间及膀胱冲洗时间明显短于PKEP组(P<0.05)。术后1、6个月,两组患者前列腺体积、RUV、QOL评分、IPSS评分低于术前.Qraax高于术前,且HoLEP组与PKEP组比较差异均有统计学意义(P<0.05)。HoLEP组患者临床总有效率为91.18%(31/34),显著高于PKEP组患者的70.59%(24/34),差异有统计学意义(X^(2)=4.660.P=0.031)。HoLEP组患者不良反应发生率为11.76%(4/34),显著低于PKEP组的35.29%(12/34),差异有统计学意义(X^(2)=5.231,P=0.022)。【结论】HoLEP术治疗老年良性BPH的临疗效果优于PKEP术,可减少住院时间,提高患者生活质量,且术后并发症少。

【Objective】To compare the short-term clinical effects of transurethral plasma enucleation of the prostate(PKEP)and transurethral holmium laser enucleation of the prostate(HoLEP)in the treatment of senile benign prostatic hyperplasia(BPH).【Methods】A total of 68 patients with BPH treated in our hospital from March 2017 to may 2019 were selected as the research objects.They were randomly divided into HoLEP group and PKEP group,with 34 cases in each group.Patients in the PKEP group were treated with PKEP and patients in the HoLEP group were treated with HoLEP.The operation,clinical efficacy and incidence of adverse reactions were compared between the two groups.【Results】The amount of intraoperative bleeding in the HoLEP group was less than that in the PKEP group,and the operation time,urinary catheter retention time,hospital stay and bladder flushing time were significantly shorter than those in the PKEP group(P<0.05).At 1 and 6 months after operation,the prostate volume,RUV,QOL score and IPSS score of the two groups were lower than those before operation,and the Qmax was higher than that before operation.There was significant difference between the HoLEP group and the PKEP group(P<0.05).The total clinical effective rate in the HoLEP group was 91.18%(31/34),which was significantly higher than 70.59%(24/34)in the PKEP group(X^(2)=4.660,P=0.031).The incidence of adverse reactions in the HoLEP group was 11.76%(4/34),which was significantly lower than 35.29%(12/34)in the PKEP group(X^(2)=5.231,P=0.022).【Conclusion】The clinical effect of HoLEP in the treatment of benign BPH in the elderly is better than PKEP.It can reduce the length of hospital stay,improve the quality of life and reduce postoperative complications.