新疆地区维吾尔族假性剥脱综合征患者眼前节参数分析比较

Analysis and comparison of anterior segment parameters in Uyghur patients with pseudoexfoliation syndrome in Xinjiang

目的探索新疆地区维吾尔族假性剥脱综合征(PEX)、剥脱性青光眼(PEXG)、原发性开角型青光眼(POAG)及年龄相关性白内障患者眼前节参数的差异。方法采用回顾性研究方法,选取2019年4月至2020年7月在中国人民解放军新疆军区总医院全军眼科中心就诊治疗的PEX患者84例(114只眼)、PEXG患者70例(96只眼)、POAG患者72例(88只眼)以及性别、年龄相匹配的年龄相关性白内障患者(对照,CON)80例(80只眼)进行研究,均为维吾尔族,分析各组患者角膜中央厚度(CCT)、前房深度(ACD)、晶状体厚度(LT)、眼轴长度(AL)、角膜曲率(水平曲率K1及垂直曲率K2)等眼前节参数的差异。结果CON、PEX、PEXG及POAG组患者性别比例及年龄比较,差异均无统计学意义(P均>0.05)。CON、PEX、PEXG及POAG组患者CCT分别为(545.52±34.22)、(536.81±42.64)、(516.74±32.39)、(530.38±28.72)μm,CON、PEX及POAG组患者均高于PEXG组(P均<0.05),PEXG组CCT变薄;CON、PEX、PEXG及POAG组患者ACD分别为(3.05±0.38)、(2.87±0.36)、(2.77±0.41)、(2.81±0.32)mm,与CON组比较,PEX、PEXG及POAG组患者ACD均较低(P均<0.05);各组患者间LT、AL、K1及K2比较差异均无统计学意义(P均>0.05)。结论新疆地区维吾尔族PEX患者ACD较CON组更浅,但PEXG患者CCT较PEX患者更薄。

Objective To explore the differences of anterior segment parameters in Uyghur patients with pseudoexfoliation syndrome(PEX),pseudoexfoliation glaucoma(PEXG),primary open-angle glaucoma(POAG)and age-related cataracts in Xinjiang.Methods A retrospective study was conducted,Uyghur patients included 114 eyes of 84 cases with PEX,96 eyes of 70 cases with PEXG,88 eyes of 72 cases with POAG and 80 eyes of 80 cases with age-related cataracts(control,CON)who had received treatment in Ophthalmology Center of Xinjiang Military Region General Hospital of Chinese People's Liberation Army from April 2019 to July 2020 were selected to obtained central corneal thickness(CCT),anterior chamber depth(ACD),lens thickness(LT),axial length(AL)and corneal curvature(horizontal curvature K1 and vertical curvature K2).Results There was no significant difference in gender ratio and age of patients between CON,PEX,PEXG and POAG groups(P>0.05).The CCT of patients in CON,PEX,PEXG and POAG groups were(545.52±34.22),(536.81±42.64),(516.74±32.39)and(530.38±28.72)μm,respectively,the CCT in CON,PEX and POAG groups were all higher than those in PEXG group(P<0.05),and the CCT in PEXG group became thinner.The ACD of patients in CON,PEX,PEXG and POAG groups were(3.05±0.38),(2.87±0.36),(2.77±0.41),(2.81±0.32)mm,respectively,compared with CON group,the ACD in PEX,PEXG and POAG groups were all lower(P<0.05).There was no significant difference in LT,AL,K1 and K2 of patients between each group(P>0.05).Conclusion This study has showed that the ACD of Uyghur patients with PEX in Xinjiang is shallower than that of CON group,but the CCT of PEXG patients is thinner than that of PEX patients.