中医方剂辅助治疗糖尿病合并脑卒中的疗效分析

Analysis of Curative Effect of TCM Prescriptions in Adjuvant Treatment of Diabetes Mellitus Complicated with Stroke

目的分析中医方剂辅助治疗糖尿病合并脑卒中的疗效。方法将该科室收治的86例糖尿病合并脑卒中的患者纳入该研究中,患者入院治疗时间为2019年10月—2021年3月,采用抛硬币方式进行分组,两组各43例。两组患者均接受了扩血管、改善脑代谢、抗凝药物、降压与降糖药物治疗,研究组加用通络熄风方治疗。比较两组患者治疗前与治疗1个月后空腹血糖、餐后2 h血糖、凝血酶原时间、D-二聚体水平、治疗总有效率。结果两组患者治疗前凝血酶原时间、D-二聚体差异无统计学意义(P>0.05),研究组患者治疗个月后凝血酶原时间、D-二聚体水平分别为(13.28±0.63)s、(0.49±0.17)μg/mL,治疗总有效率为93.02%,均优于对照组,差异有统计学意义(P<0.05);两组患者治疗前空腹血糖、餐后2 h血糖差异无统计学意义(P>0.05),研究组患者治疗1个月后空腹血糖、餐后2 h血糖分别为(6.39±0.68)、(8.31±0.82)mmol/L,优于对照组的(9.41±0.73)、(10.14±0.97)mmol/L,差异有统计学意义(P<0.05);两组患者治疗前神经功能缺损评分差异无统计学意义(P>0.05),研究组患者治疗1个月后神经功能缺损评分为(8.78±1.03)分,优于对照组的(12.65±1.16)分,差异有统计学意义(P<0.05)。结论使用中医方剂辅助治疗糖尿病合并脑卒中患者疗效确切,可以更有效控制患者血糖,可以改善患者凝血功能,并且改善患者的神经功能。

Objective Analyze the curative effect of TCM prescriptions in adjuvant treatment of diabetes mellitus complicated with stroke.Methods The 86 patients with diabetes and stroke admitted to the undergraduate room were included in this study.The patients were admitted to the hospital for treatment from October 2019 to March 2021.They were divided into groups by tossing a coin,with 43 cases in each group.Both groups of patients were treated with vasodilators,improving brain metabolism,anticoagulant drugs,blood pressure lowering and hypoglycemic drugs,and the study group was treated with Tongluo Xifeng decoction.The fasting blood glucose,2 hours postprandial blood glucose,prothrombin time,D-dimer level,and total effective rate of treatment were compared between the two groups of patients before treatment and one month after treatment.Results There was no significant difference in prothrombin time and D-dimer before treatment between the two groups(P>0.05).The prothrombin time and D-dimer level of patients in the study group were(13.28±0.63) seconds and(0.49±0.17)μg/mL respectively after one month of treatment,and the total effective rate of treatment was 93.02%.Both were better than the control group,the difference was statistically significant(P<0.05);there was no significant difference in fasting blood glucose before treatment and 2 h postprandial blood glucose between the two groups(P>0.05).The fasting blood glucose and 2 h postprandial blood glucose of the study group after one month of treatment were(6.39±0.68)mmol/L and(8.31±0.82)mmol/L,respectively,which was better than the control group(9.41±0.73)mmol/L and(10.14±0.97)mmol/L,the difference was statistically significant(P<0.05);there was no significant difference in neurological deficit scores between the two groups of patients before treatment(P>0.05).The neurological deficit scores of patients in the study group were(8.78±1.03)points after one month of treatment,which was better than the control group(12.65±1.16)points,and the difference was statistically significant(P<0.05).Conclusion The use of traditional Chinese medicine prescriptions to assist patients with diabetes and stroke has a definite effect,can more effectively control the patient’s blood glucose,can improve the patient’s blood coagulation function,and improve the patient’s neurological function.