甲巯咪唑诱发粒细胞缺乏及噬血细胞综合征一例报道

Methimazole induced agranulocytosis and hemophagocytic syndrome: One case report

通过分析1例甲状腺功能亢进症(以下简称甲亢)患者服甲巯咪唑后出现粒细胞缺乏继发噬血细胞综合征的少见病例,探讨临床工作中的诊治经验,以提高诊治水平。该患者服用甲巯咪唑后出现粒细胞缺乏合并感染,经过治疗后短暂好转,但迅速因感染进展为噬血细胞综合征,经过地塞米松治疗后病情好转。

In order to improve the level of diagnosis and treatment,we report a rare case of hyperthyroidism patient occurred agranulocytosis and hemophagocytic syndrome after taking methimazole.After methimazole treatment,agranulocytosis and infection was developed,but was improved temporarily after treatment.However because of infection,the condition was rapidly developed into hemophagocytic syndrome.Finally,the patient improved rapidly with the treatment of dexamethasone.