胺碘酮在急性心肌梗死合并心房颤动治疗中的效果分析

Analysis of the effect of amiodarone in the treatment of acute myocardial infarction combined with atrial fibrillation

目的 探究胺碘酮治疗急性心肌梗死合并心房颤动患者的临床效果。方法 80例急性心肌梗死合并心房颤动患者,采用随机数字表法分为实验组与参照组,每组40例。参照组患者采用普罗帕酮治疗,实验组患者采用胺碘酮治疗。比较两组患者治疗后不同时间的心率、治疗前后生活质量评分及治疗效果。结果 治疗后1、2、24 h,实验组患者心率分别为(125.23±0.23)、(105.06±0.55)、(87.44±0.23)次/min,均低于参照组的(132.89±0.44)、(126.46±0.43)、(108.46±0.44)次/min,差异具有统计学意义(P<0.05)。治疗后,实验组患者日常活动、社交活动评分分别为(97.96±0.55)、(92.44±0.45)分,均高于参照组的(89.46±0.43)、(85.46±0.56)分,差异具有统计学意义(P<0.05)。实验组患者治疗总有效率为90.00%,高于参照组的70.00%,差异具有统计学意义(P<0.05)。结论 对急性心肌梗死合并心房颤动患者采用胺碘酮治疗效果显著,能够改善患者的心率,提高生活质量,值得在临床中推广应用。

Objective To investigate the clinical effect of amiodarone in the treatment of acute myocardial infarction combined with atrial fibrillation.Methods A total of 80 patients with acute myocardial infarction and atrial fibrillation were divided into experimental group and reference group by random numerical table,with 40 cases in each group.Patients in the reference group were treated with propafenone,and patients in the experimental group were treated with amiodarone.Both groups were compared in terms of heart rate at different time points after treatment,quality of life scores before and after treatment,and the therapeutic effect.Results 1,2,24 h after treatment,the heart rates of the experimental group were(125.23±0.23),(105.06±0.55),and(87.44±0.23)beats/min,which were lower than(132.89±0.44)and(126.46±0.43),(108.46±0.44)beats/min of the reference group,and the difference was statistically significant(P<0.05).After treatment,the scores of daily activities and social activities of the experimental group were(97.96±0.55)and(92.44±0.45)points,which were higher than(89.46±0.43)and(85.46±0.56)points of the reference group,and the difference was statistically significant(P<0.05).The total effective rate of treatment in the experimental group was 90.00%,which was higher than 70.00%in the reference group,and the difference was statistically significant(P<0.05).Conclusion Amiodarone has significant effect on patients with acute myocardial infarction and atrial fibrillation,and it can improve the heart rate and improve the quality of life of patients.It is worthy of clinical promotion and application.