美托洛尔联合胺碘酮治疗快速性心律失常的临床疗效分析

Clinical efficacy of metoprolol combined with amiodarone in the treatment of tachyarrhythmia

目的 分析快速性心律失常应用胺碘酮与美托洛尔联合治疗的效果。方法 106例快速性心律失常患者,以随机抽签法分为观察组与对照组,每组53例。对照组采取胺碘酮单药治疗,观察组采取胺碘酮联合美托洛尔治疗。比较两组干预前后重要生命体征、临床疗效。结果 干预后,观察组收缩压、舒张压、心率分别为(111.28±2.24)mm Hg(1 mm Hg=0.133 kPa)、(76.31±1.51)mm Hg、(73.49±1.48)次/min,均低于对照组的(138.26±1.63)mm Hg、(89.31±1.11)mm Hg、(87.83±1.44)次/min,差异有统计学意义(P<0.05)。观察组治疗总有效率94.34%高于对照组的77.37%,差异有统计学意义(P<0.05)。结论 快速性心律失常应用胺碘酮与美托洛尔联合用药治疗方案,能有效改善患者的生命体征,实现症状缓解及疗效提升,临床指导意义显著,值得推行实践。

Objective To analyze the effect of metoprolol combined with amiodarone in the treatment of tachyarrhythmia.Methods A total of 106 patients with tachyarrhythmia were randomly divided into observation group and control group,with 53 cases in each group.The control group was treated with amiodarone alone,and the observation group was treated with amiodarone and metoprolol.The important vital signs before and after the intervention and clinical efficacy were compared between the two groups.Results After the intervention,the systolic blood pressure,diastolic blood pressure,and heart rate of the observation group were(111.28±2.24)mm Hg(1 mm Hg=0.133 kPa),(76.31±1.51)mm Hg,and(73.49±1.48)beats/min,which were all lower than(138.26±1.63)mm Hg,(89.31±1.11)mm Hg,and(87.83±1.44)times/min of the control group,and the difference was statistically significant(P<0.05).The total effective rate of treatment 94.34%in the observation group was higher than 77.37%in the control group,and the difference was statistically significant(P<0.05).Conclusion The combination of amiodarone and metoprolol has significant clinical guidance in the treatment of tachyarrhythmia,which can effectively improve the vital signs,relieve symptoms and enhance the efficacy of patients,and it is worthy of promotion and application.