黄芪桂枝五物汤辅助治疗脑梗死恢复期患者的效果分析

Effect of Huangqi Guizhi Wuwu Decoction on patients with cerebral infarction in convalescence

目的 探究黄芩桂枝五物汤辅助治疗脑梗死恢复期患者的临床效果。方法 86例脑梗死恢复期患者,依据治疗方法不同分为对照组和观察组,各43例。对照组接受常规西药治疗,观察组在常规西药治疗基础上接受黄芪桂枝五物汤辅助治疗。比较两组治疗效果,治疗前后神经缺损情况、脑血液流变学指标,不良反应发生情况。结果 观察组治疗总有效率为97.67%,高于对照组的86.05%,差异具有统计学意义(P<0.05)。治疗后,观察组美国国立卫生研究院卒中量表(NIHSS)评分(8.38±1.07)分低于对照组的(9.00±1.35)分,差异具有统计学意义(P<0.05)。治疗后,观察组脑部血流速度(15.74±1.32)cm/s、椎动脉血流量(148.77±21.30)ml/min、基底动脉血流量(273.54±21.33)ml/min均优于对照组的(14.96±1.10)cm/s、(131.85±24.64)ml/min、(259.87±18.46)ml/min,差异有统计学意义(P<0.05)。观察组不良反应发生率为13.95%,与对照组的11.63%比较,差异无统计学意义(P>0.05)。结论 对脑梗死恢复期患者应用黄芪桂枝五物汤辅助治疗可提升治疗效果,改善患者脑组织血流灌注能力,降低其神经功能缺损,治疗效果安全理想,具深入研究价值。

Objective To discuss the clinical effect of Huangqi Guizhi Wuwu Decoction on patients with cerebral infarction in convalescence.Methods A total of 86 patients with cerebral infarction in convalescence were divided into control group and observation group according to different treatment methods,with 43 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with Huangqi Guizhi Wuwu Decoction on the basis of conventional western medicine.Both groups were compared in terms of therapeutic effect,neurological deficits and cerebral hemorheology indexes before and after treatment,occurrence of adverse reactions.Results The total effective rate of treatment in the observation group was 97.67%,which was higher than 86.05%in the control group,and the difference was statistically significant(P<0.05).After treatment,the National Institutes of Health stroke scale(NIHSS)scores(8.38±1.07)points of the observation group was lower than(9.00±1.35)points of the control group,and the difference was statistically significant(P<0.05).After treatment,the blood flow velocity,vertebral artery blood flow and basal artery blood flow of the observation group were(15.74±1.32)cm/s,(148.77±21.30)ml/min and(273.54±21.33)ml/min,which were better than(14.96±1.10)cm/s,(131.85±24.64)ml/min and(259.87±18.46)ml/min of the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 13.95%,which was not statistically different from 11.63%in the control group(P>0.05).Conclusion The application of Huangqi Guizhi Wuwu Decoction to patients with cerebral infarction in convalescence can enhance the therapeutic effect,improve the blood perfusion capacity of cerebral tissues,and reduce their neurological deficits,with safe and ideal therapeutic effect,which is of in-depth study value.