摘要
吡喹酮除具有广谱抗吸虫和绦虫作用外,还具有调节炎症反应、抗纤维化等药理作用。本文综述了吡喹酮抗肝纤维化作用及其机制,以期为吡喹酮用于肝纤维化治疗提供理论依据。
Praziquantel not only has broad-spectrum anti-trematode and anti-tapeworm effects, but also has pharmacological effects such as regulating inflammatory response and anti-fibrosis. Hereby, the anti-fibrosis effect of praziquantel and its mechanism were reviewed in order to provide theoretical basis for the treatment of liver fibrosis.
作者
袁轩
戴建荣
YUAN Xuan;DAI Jian-Rong(Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention,Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology,Jiangsu Institute of Parasitic Diseases,Wuxi 214064,China)
出处
《中国血吸虫病防治杂志》
CAS
CSCD
北大核心
2021年第5期540-543,共4页
Chinese Journal of Schistosomiasis Control
基金
国家重点研发计划(2020YFC1200100)。
关键词
吡喹酮
血吸虫病
肝纤维化
Praziquantel
Schistosomiasis
Hepatic fibrosis
