无溶剂条件下利用Henry缩合反应高效便捷制备β-硝基苯乙烯衍生物

Efficient and convenient preparation ofβ-nitrostyrene derivatives by using Henry condensation under ecologically benign solvent-free conditions

报道了温和、绿色条件下,利用Henry缩合反应高效便捷制备β-硝基苯乙烯衍生物的方法.该方法主要利用环境友好的功能化离子液体代替常规的酸碱催化剂,无溶剂条件下进行了催化合成,高效地促进了芳香醛的转化,高产率地制得了β-硝基苯乙烯衍生物.此外,该离子液体可以在反应后近乎定量地回收.

An effective and convenient preparation method ofβ-nitrostyrene derivatives by using Henry condensation under mild and green conditions was presented.The essential advantage of this method was solvent-free,which employed environmentally benign functionalized ionic liquid as catalyst instead of conventional applied acids or bases.The method could attain good to excellent conversion of the aromatic aldehydes and high yields of the correspondingβ-nitrostyrene derivatives.Furthermore,the ionic liquid could be quantitatively recovered after the reaction.