晚期上皮性卵巢癌初始治疗相关预测手段研究进展

Advances in research on predictive methods related to initial treatment of advanced epithelial ovarian cancer

上皮性卵巢癌(卵巢癌)以初始肿瘤细胞减灭术作为首选治疗方案,并得到指南的优先推荐,对于某些晚期患者,新辅助化疗的疗效亦得到肯定,但其适应证仍存在主观上的不同认知。因此,迫切需要客观预测手段指导优化病例的选择,使治疗达到风险与获益的统一。本文将就晚期卵巢癌初始治疗及预后相关预测手段进行综述,为临床实践提供参考。

Primary debulking surgery(PDS),as the preferred treatment for advanced epithelial ovarian cancer,is recommended by existing guidelines.In some advanced cases,the efficacy of neoadjuvant chemotherapy has also been affirmed.However,there are still different subjective cognitions for its indications.Therefore,there is an urgent need for objective prediction methods to guide and to optimize the selection of cases so as to achieve the unity of risks and benefits.This article will review the initial treatment and prognostic prediction methods of ovarian cancers to provide a reference guide for clinical practice.