个性化添加母乳强化剂对早产儿生长发育的影响

The Effect of Personalized Breast Milk Fortifier on the Growth and Development of Premature Infants

目的:探究个性化添加母乳强化剂对早产儿生长发育及并发症发生率的影响。方法:选择2020年4月至2021年4月期间出生后24 h内转入南京医科大学附属无锡市儿童医院的86例早产儿,根据喂养方式的不同将早产儿分为对照组(标准母乳强化剂喂养)与观察组(个性化添加母乳强化剂喂养),各43例。观察两组早产儿喂养前后生长发育情况、血清生化指标及住院期间相关并发并发症发生率。结果:喂养后观察组早产儿体质量、身长和头围均高于对照组,差异具有统计学意义(P<0.05);喂养后观察组早产儿的血清前白蛋白(PA)、碱性磷酸酶(ALP)、白蛋白(ALB)及尿素氮(BUN)水平均高于对照组,差异具有统计学意义(P<0.05);两组早产儿住院期间相关并发症发生率比较,差异无统计学意义(P>0.05)。结论:个性化添加母乳强化剂能够促进早产儿机体的生长发育,提升早产儿机体营养水平,具有较高的安全性,能够保障患儿健康生长。

Objective To explore the effects of personalized breast milk fortifiers on the growth and development of premature infants and the incidence of complications.Methods A total of 86 preterm infants who were transferred to Wuxi Children’s Hospital of Nanjing Medical University within 24 hours after birth between April 2020 and April 2021 were selected.The preterm infants were divided into control groups according to different feeding methods(standard breast milk fortification).Remedy feeding and observation group(individualized feeding with breast milk fortifier),43 cases in each.Observe the growth and development of premature infants before and after feeding,serum biochemical indicators and the incidence of related complications during hospitalization.Results After feeding,the weight,length and head circumference of premature infants in the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05);the levels of PA,ALP,ALB and BUN of premature infants in the observation group after feeding were higher than those in the control group.In the control group,the difference was statistically significant(P<0.05);there was no statistically significant difference in the incidence of complications between the two groups of preterm infants during hospitalization(P>0.05).Conclusion The personalized addition of breast milk fortifiers can promote the growth and development of premature infants,and improve the nutritional level of premature infants.It has high safety and can ensure the healthy growth of children.