裸花紫珠胶囊治疗Ⅰ期内痔患者的临床疗效观察

Clinical Efficacy Observation of Luohua Zizhu Capsule in the Treatment of Stage I Internal Hemorrhoids

目的:探讨裸花紫珠胶囊治疗Ⅰ期内痔患者的临床疗效。方法:选择遵义市第一人民医院2018年1月至2018年12月期间收治的200例I期内痔患者,随机数字表法将患者分成对照组和观察组,各100例。对照组用常规药物治疗,观察组用常规药物联合裸花紫珠胶囊治疗,比较两组患者的症状与体征改善情况和治疗总有效率,记录两组患者的肛门异物感和肛门坠胀、肛门肿痛等临床表现的消失时间,观察两组患者用药期间发生的消化道症状和血尿粪常规异常等不良反应。结果:观察组患者治疗总有效率为97.0%,高于对照组的86.0%,差异具有统计学意义(P<0.05);治疗后,观察组患者的肛门异物感和肛门坠胀、肛门肿痛以及间歇性便时肛门出血的消失时间短于对照组,差异具有统计学意义(P<0.05);两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:I期内痔患者用裸花紫珠胶囊治疗的效果显著,能促使患者的症状和体征在短时间内改善、消失,加快患者病情的康复,且不良反应少。

Objective To explore the clinical efficacy of Luohua Zizhu capsule in the treatment of stage I internal hemorrhoids.Methods 200 patients with stage I hemorrhoids treated in Zunyi first people's Hospital from January 2018 to December 2018 were randomly divided into control group and observation group,with 100 cases in each group.The control group was treated with conventional drugs and the observation group was treated with conventional drugs combined with naked flower Zizhu capsule.The improvement of symptoms and signs and the total effective rate of treatment were compared between the two groups.The disappearance time of anal foreign body feeling,anal distension,anal swelling and pain and other clinical manifestations of the two groups were recorded,The gastrointestinal symptoms and routine abnormalities of hematuria and feces in the two groups were observed.Results The total effective rate of the observation group was 97.0%,higher than 86.0%of the control group(P<0.05);The disappearance time of anal foreign body sensation,anal distension,anal swelling and pain and intermittent anal bleeding in the observation group was shorter than that in the control group(P<0.05);There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of Luohua Zizhu capsule in the treatment of patients with stage I internal hemorrhoids is significant,which can promote the improvement and disappearance of patients'symptoms and signs in a short time,accelerate the recovery of patients'condition,and have less adverse reactions.