罂粟碱注射液治疗急性脑梗死的疗效观察

Observation of Therapeutic Effect of Papaverine Injection on Acute Cerebral Infarction

目的:观察罂粟碱注射液治疗急性脑梗死的临床疗效。方法:纳入2019年1月至2020年2月东莞市清溪医院收治的86例急性脑梗死患者作为研究对象,随机分为常规组和罂粟碱组,两组各43例。常规组给予脉络宁注射液、阿司匹林肠溶片进行治疗,罂粟碱组给予脉络宁注射液、阿司匹林肠溶片联合罂粟碱注射液进行治疗。观察两组患者病情改善优良率,神经功能缺损评分〔美国国立卫生研究院脑卒中量表(NIHSS)评分〕。结果:治疗后,罂粟碱组患者病情改善优良率为93.02%,相比常规组的76.74%更高,差异具有统计学意义(P<0.05)。治疗后,罂粟碱组患者NIHSS评分为(12.07±2.15)分,相比常规组的(19.18±3.74)分更低,差异具有统计学意义(P<0.05)。结论:罂粟碱注射液治疗急性脑梗死可有助于改善患者的病情,促进神经功能恢复。

Objective To observe the clinical efficacy of papaverine injection in the treatment of acute cerebral infarction.Methods A total of 86 patients with acute cerebral infarction admitted to Qingxi Hospital in Dongguan City from January 2019 to February 2020 were enrolled as the research subjects,and were randomly divided into two groups,the routine group and the papaverine group,with 43 cases in each group.The routine group was given Mailuoning injection and aspirin enteric-coated tablets for treatment,and the papaverine group was given Mailuoning injection,aspirin enteric-coated tablets combined with papaverine injection for treatment.Observe the improvement rate and neurological deficit score of the two groups[National Institutes of Health Stroke Scale(NIHSS)score].Results After treatment,the excellent and good rate of patients in the papaverine group was 93.02%,which was higher than 76.74%in the conventional group.The difference was statistically significant(P<0.05).After treatment,the NIHSS score(12.07±2.15)of the papaverine group was lower than that of the conventional group(19.18±3.74),and the difference was statistically significant(P<0.05).Conclusion Papaverine injection has a significant clinical effect on acute cerebral infarction.