胺碘酮联合利多卡因治疗急性心肌梗死伴室性心律失常的疗效

Efficacy of Amiodarone and Lidocaine in the Treatment of Acute Myocardial Infarction with Ventricular Arrhythmia

目的:观察胺碘酮联合利多卡因治疗急性心肌梗死伴室性心律失常的疗效。方法:回顾性选取洛阳东方医院2018年4月至2020年4月收治的76例治疗急性心肌梗死伴室性心律失常患者为研究对象,按照是否应用胺碘酮联合利多卡因方案给药治疗将患者分为对照组(38例,给予利多卡因治疗)与观察组(38例:应用联合用药方案),比较两组患者治疗效果。结果:观察组患者给药后QT离散度显著低于对照组、P-R间期显著高于对照组,差异具有统计学意义(P<0.05)。观察组患者给药后总有效率(94.74%)显著高于对照组(73.68%),差异具有统计学意义(P<0.05)。观察组患者给药期间不良反应发生率(10.53%)低于对照组(28.95%),差异具有统计学意义(P<0.05)。结论:急性心肌梗死伴室性心律失常患者胺碘酮联合利多卡因方案给药治疗效果优于利多卡因给药治疗效果。

Objective To observe the efficacy of amiodarone and lidocaine in the treatment of acute myocardial infarction with ventricular arrhythmia.Methods A retrospective selection of Luoyang Oriental Hospital between April 2018 and April 2020 were analyzed in 76 cases of the treatment of acute myocardial infarction(mi)and ventricular arrhythmia patients as the research object,according to whether the application of amiodarone and lidocaine medication divided the patients into control group(38 cases:no application,the plan of the given lidocaine treatment)and the observation group(38 cases:The treatment effect was compared between the two groups.Results After medication,QT dispersion in observation group was significantly lower than that in control group,and P-R interval was significantly higher than that in control group,with statistical significance(P<0.05).The total effective rate of observation group(94.74%)was significantly higher than that of control groupb(73.68%),the difference was statistically significant(P<0.05).The incidence of adverse reactions in observation group(10.53%)was lower than that in control group(28.95%),the difference was statistically significant(P<0.05).Conclusion The therapeutic effect of amiodarone and lidocaine is better than that of lidocaine in acute myocardial infarction patients with ventricular arrhythmia.