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缺血修饰白蛋白、前白蛋白联合检测对急性冠脉综合征的诊断价值分析

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摘要 目的研究缺血修饰白蛋白(IMA)、前白蛋白(PA)联合检测对急性冠脉综合征(ACS)患者的临床诊断价值,为其临床诊治提供依据。方法选取包头市中心医院2019年4月至2020年4月收治的123例ACS患者作为观察组,根据患者疾病类型分为不稳定心绞痛(UA)组(47例)、ST段抬高型心肌梗死(STEMI)组(44例)及非ST段抬高型心肌梗死(NSTEMI)组(32例),另选取同期进行冠状动脉造影检查排除ACS诊断的30例健康体检者作为对照组,开展前瞻性研究。比较两组研究对象血清IMA、PA水平;比较不同分型ACS患者血清IMA、PA水平;比较血清IMA、PA单独及联合检测ACS的诊断效能。结果观察组患者血清IMA水平显著高于对照组;PA水平显著低于对照组;UA组、STEMI组及NSTEMI组患者IMA水平均显著高于对照组,NSTEMI组显著高于STEMI组、UA组,STEMI组显著高于UA组;UA组、STEMI组及NSTEMI组患者PA水平均显著低于对照组(均P<0.05),NSTEMI、STEMI组、UA组患者PA水平比较,差异无统计学意义(P>0.05);IMA、PA两者联合对ACS诊断的特异度、灵敏度均显著高于PA单独诊断。结论ACS患者血清IMA水平异常升高,PA水平异常降低,同时,IMA、PA两者联合诊断可显著提高对ACS的诊断灵敏度与特异度,临床诊断价值较高。
作者 张琪 赵美丽
出处 《现代医学与健康研究电子杂志》 2021年第21期66-68,共3页 Modern Medicine and Health Research
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