粪便隐血试验联合肿瘤标志物检测在结直肠癌诊断中的应用

Fecal Occult Blood Test Combined with Tumor-marks Detection in Diagnosing Colorectal Cancer

为探讨粪便隐血试验联合肿瘤标志物检测在结直肠癌诊断中的应用效果,回顾性分析本院68例疑似结直肠癌患者临床资料。所有患者入院后均行粪便隐血试验联合肿瘤标志物检测,分析粪便隐血试验联合肿瘤标志物检测诊断结直肠癌的准确率,并与病理检查结果进行对照观察。结果显示,所有患者经病理诊断确诊为结直肠癌63例,其中结肠癌42例,直肠癌21例。经粪便隐血试验检出结直肠癌54例,肿瘤标志物检出结直肠癌58例,联合检测检出结直肠癌61例,与病理检查结果比较差异无统计学意义(P>0.05)。结直肠癌患者肿瘤标志物水平明显高于正常值,也高于5例非结直肠癌患者,差异有显著统计学意义(P <0.01)。结果表明,粪便隐血试验联合肿瘤标志物检测可实现对结直肠癌的检出,能够为临床诊治工作提供科学的参考,是值得推荐的结直肠癌联合检测手段。

This study was to investigate the efficacy of fecal occult blood test(FOBT)combined with tumor-marks detection in diagnosing colorectal cancer,author reviewed and analysed the clinical data of 68 cases suspected as colorectal cancer treated in author’s hospital who had all received FOBT plus tumormarks detection,evalunted above combined inspection’s accuracy rate,and compared to pathological examination results.As results,in 68 cases,the pathological exam.results of 63 cases were of colorectal cancer(colonic cancer,42 cases;rectal cancer,21 cases),meanwhile the FOBT’results in 54 cases were of colorectal cancer,the tumor-marks detection results in 58 cases were of colorectal cancer,and above both combined results 61 cases were of colorectal cancer,which there was no statistical difference between the four results and the pathological exam.one(P >0.05);but,the tumor-marks levels of colorectal cancer patients were significantly higher than normal value,also did than non-colorectal cancer patients’ levels(P <0.05).Results show that FOBT combined tumor-marks detection is worthy to be recommended as combined detection tool for colorectal cancer.