自身免疫性垂体炎发病机制的研究进展

Research Progress on the Pathogenesis of Autoimmune Hypophysitis

自身免疫性垂体炎(AH)是一种罕见的垂体炎性疾病。其临床表现主要以垂体内分泌异常或炎症压迫为特征,典型症状为头痛、视觉受压、多饮、多尿等,并可伴有其他自身免疫性疾病。尽管进行了大量研究,但AH的发病机制尚未完全阐明。因此本文讨论了最近关于自身免疫性垂体炎的潜在机制的发现,以深刻理解AH发生发展的病理生理过程,并可能为AH的诊断和治疗提供新的方向。

Autoimmune hypophysitis(AH)is a rare inflammatory disease of the pituitary gland.Its clinical manifestations are mainly characterized by abnormal pituitary secretion or inflammatory compression.The typical symptoms are headache,visual stress,polydipsia,polyuria,etc,and may be accompanied by other autoimmune diseases.Despite extensive research,the pathogenesis of AH has not yet been fully elucidated.This article discusses the recent discoveries about the underlying mechanism of autoimmune hypophysitis,in order to deeply understand the pathophysiological process of the occurrence and development of AH,and may provide a new direction for the diagnosis and treatment of AH.