羊栖菜多糖的提取纯化及功能活性研究进展

Research progress on extraction,purification and functional activity of Sargassum fusiforme polysaccharides

羊栖菜是一种重要的经济藻类,主要分布在我国浙江、福建等地。羊栖菜含有丰富的多糖,主要包括褐藻胶、褐藻多糖硫酸脂以及褐藻淀粉等,是一种可溶于水的酸性多糖,具有良好生物活性。羊栖菜多糖的制备可以通过水提醇沉、酸提、酶提及超声波辅助等提取方法获得,然而不同提取方法制备的多糖得率、结构及功能活性不尽相同。目前对羊栖菜多糖的药理活性研究主要集中在抗肿瘤、抗氧化、降血糖、抗衰老、调节肠道菌群、抗病毒等方面,提示羊栖菜多糖在医药、功能食品领域有着良好的前景。本文就国内外羊栖菜多糖的提取纯化及功能活性研究进行了系统的归纳和总结,旨在为羊栖菜多糖的靶向功能提取纯化研究提供参考。

Sargassum fusiforme is an important economic algae,mainly distributed in Zhejiang,Fujian and other places.Sargassum fusiforme contains more polysaccharides,which mainly include alginate,alginate polysaccharide sulfate and alginate starch.It is an acidic polysaccharide soluble in water and has good biological activity.The preparation of polysaccharides from Sargassum fusiforme can be obtained by water extraction and alcohol precipitation,acid extraction,enzyme extraction and ultrasonic-assisted extraction.However,the yield,structure and functional activity of polysaccharides prepared by different extraction methods are different.At present,people mainly studied the anti-tumor,anti-oxidation,hypoglycemic,anti-aging,regulating intestinal flora,antiviral and other pharmacological activities of polysaccharides from Sargassum fusiforme,indicating that polysaccharides from Sargassum fusiforme have good prospects in the field of medicine and functional food.Therefore,this paper systematically summarized the extraction,purification and functional activities of polysaccharides from Sargassum fusiforme in China and abroad,aiming to provide reference for the extraction and purification of targeted functions of polysaccharides from Sargassum fusiforme.