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联合检测连续2点超声与D-D诊断下肢骨折术后疑似血栓的临床意义 被引量:2

Clinical significance of combined detection of continuous 2-point ultrasound and D-D in the diagnosis of suspected thrombosis after lower extremity fractures
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摘要 目的:分析连续2点超声与D-二聚体(D-D)联合检测对下肢骨折术后疑似血栓的诊断价值。方法:选取2019年1—10月我院下肢骨折患者125例,均行择期手术,根据术后是否发生血栓分为血栓组(n=44)、未发生血栓组(n=81)。均行连续2点超声检查、血浆D-D水平检测,比较两组术后1、3、7 d股总静脉(CFV)及腘静脉(POV)血流速度、血浆D-D水平,探讨CFV、POV血流速度与血浆D-D水平相关性,分析连续2点超声、D-D联合对下肢骨折术后血栓的诊断价值。结果:血栓组术后3、7 d血浆D-D水平高于未发生血栓组,CFV、POV血流速度低于未发生血栓组(P<0.05);CFV、POV血流速度与血浆D-D水平呈负相关性(P<0.05);术后7 d血浆D-D水平、CFV、POV血流速度联合诊断下肢骨折术后血栓曲线下面积最大,为0.877,敏感性为93.18%,特异性为69.14%。结论:血浆D-D水平、连续2点超声联合检测可为临床诊断下肢骨折术后血栓、实施对症治疗提供有效辅助手段。 Objective:To analyze the diagnostic value of combined detection of continuous 2-point ultrasound and D-dimer(D-D)for suspected thrombosis after lower limb fractures.Methods:From January 2019 to October 2019,125 patients with lower limb fractures in our hospital were selected for elective surgery,they were divided into thrombus group(n=44)and non-thrombosis group(n=81)according to whether thrombosis occurred after surgery.All patients underwent continuous 2-point ultrasonography and plasma D-D level detection.The blood flow velocity of common femoral vein(CFV)and popliteal vein(POV)and plasma D-D level were compared between the two groups at 1,3,and 7 days after operation.The correlation between CFV and POV blood flow velocity and plasma D-D level was explored,and the diagnostic value of continuous 2-point ultrasound and D-D combined for thrombosis after lower limb fracture surgery was analyzed.Results:The plasma D-D level of the thrombus group was higher than that of the non-thrombosis group at 3 and 7 days after operation,and the blood flow velocity of CFV and POV was lower than that of the non-thrombosis group(P<0.05).The blood flow velocity of CFV and POV was negatively correlated with plasma D-D level(P<0.05).The area under the curve for the combined diagnosis of postoperative thrombosis of lower extremity fracture by plasma D-D level,CFV and POV blood flow velocity was the largest at 0.877,the sensitivity was 93.18%,and the specificity was 69.14%.Conclusion:The combined detection of plasma D-D level and continuous 2-point ultrasound can provide effective auxiliary means for clinical diagnosis of postoperative thrombosis of lower limb fractures and symptomatic treatment.
作者 路鑫铭 张志友 王蕾 刘丽清 杨菲 崔敬先 蔡金生 LU Xin-ming;ZHANG Zhi-you;WANG Lei;LIU Li-qing;YANG Fei;CUI Jing-xian;CAI Jin-sheng(North China Medical Xingtai General Hospital,Xingtai Hebei 054000,China)
出处 《中国临床医学影像杂志》 CAS CSCD 2021年第11期823-826,共4页 Journal of China Clinic Medical Imaging
基金 邢台市重点研发项目(2020ZC380)。
关键词 下肢 骨折 血栓形成 超声检查 多普勒 彩色 Lower Extremity Fractures Bone Thrombosis Ultrasonography Doppler Color
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