小梁切除术联合抗代谢药物应用治疗新生血管性青光眼效果评价

Evaluation of the Effects of Glaucoma Surgery Combined with Antimetabolic Drugs in the Treatment of Neovascular Glaucoma

目的:探讨小梁切除术联合抗代谢药物治疗新生血管性青光眼的临床疗效。方法:选择我院2017年6月至2019年8月收治的62例(62眼)患者作为研究对象,将患者按照治疗方法的不同分为对照组与观察组,对照组患者进行小梁切除术,观察组在对照组基础上给予丝裂霉素与干扰素联合治疗,比较两组治疗效果。结果:与术前相比,两组患者在术后一周眼压大幅下降,且术后一周、术后6个月,观察组患者眼压显著低于对照组,差异显著(P<0.05),且观察组有效率为87.5%,显著高于对照组的63.3%,差异显著(P<0.05)。结论:小梁切除术联合抗代谢药物的使用能提高治疗效果,对眼压控制效果好,且能提高患者视力,可行性更高,值得临床推广。

Objective:To investigate the clinical effect of trabeculectomy combined with antimetabolic drugs in the treatment of neovascular glaucoma.Method:62 patients(62 eyes)in our hospital from June 2017 to August 2019 were selected as the research objects,patients were divided into control group and observation group according to different treatment methods,the control group was treated with trabeculectomy,the observation group was treated with mitomycin and interferon on the basis of the control group,the therapeutic effects of the two groups were compared.Result:The intraocular pressure of the two groups decreased significantly one week after operation,The intraocular pressure in the observation group was significantly lower than that in the control group one week and six months after the operation(P<0.05),The effective rate of the observation group was 87.5%,which was significantly higher than 63.3%of the control group(P<0.05).Conclusion:Trabeculectomy combined with the use of antimetabolic drugs can improve the therapeutic effect,control the intraocular pressure,and improve the visual acuity of patients,which is more feasible and worthy of clinical promotion.