深圳宝安地区无偿献血人群新冠病毒抗体筛查研究

Research of antibody screening for SARS-CoV-2 in blood donors in Bao'an area of Shenzhen

目的了解深圳宝安地区无偿献血人群新冠病毒感染血清抗体水平,评估人群感染状况、献血前新冠病毒相关健康状况征询的有效性及疫情期间血液质量情况,以保证输血安全及改进无偿献血工作。方法胶体金免疫层析法检测2020年4月11日至5月12日宝安地区无偿献血3331份血液标本的新冠病毒lgG/lgM抗体,抗体阳性标本送宝安区CDC进行新冠病毒核酸检测。结果新冠病毒抗体阳性率为0.57%(19/3331),19份新冠病毒抗体阳性标本再进行新冠病毒核酸检测结果均为阴性。结论实验结果提示本站血液质量安全在控,前期开展的献血招募前新冠病毒相关健康状况征询可有效劝阻存在新冠病毒高风险人群献血,可减少输血安全隐患。

Objective To investigate SARS-CoV-2 antibody level in blood donors in Bao′an area of Shenzhen,characterize the current infection status of SARS-CoV-2 in blood donors,assess the effects of health survey and evaluate the blood quality during the outbreak.So as to ensure the safety of blood transfusion and improve our work.Methods Colloidal gold immunochromatography was used to perform screening for lgG/lgM antibody of SARS-CoV-2 on 3331 samples from blood donors,recorded from April 11,2020 to May 12,2020 in Bao′an area.The antibody positive samples were sent to CDC in Bao′an for nucleic acid detection of SARS-CoV-2.Results The positive rate of antibody of SARS-CoV-2 was 0.57%(19/3331),and the nucleic acid test of 19 samples with positive antibody was negative.Conclusion The experimental results suggest that we can ensure the blood quality and safety.The health survey before blood donation for blood donors can effectively discourage the blood donation of high-risk patients with SARS-CoV-2 and reduce the danger of blood transfusion.