经支气管镜冷冻肺活检检测技术对肺部弥散性疾病患者病理诊断的作用分析

Analysis of the effect of TBCB on pathological diagnosis of pulmonary diffuse disease

目的研究经支气管镜冷冻肺活检(TBCB)检测技术对肺部弥散性疾病患者病理诊断的作用。方法将该院从2017年2月至2020年2月收治的肺部弥散性疾病患者79例纳入研究,所有受试者均开展TBCB检测以及胸腔镜肺部活检。比较两种检测方式对肺部弥散性疾病的检出情况,术后并发症发生情况,医疗费用以及术后住院时长,患者满意度等方面的影响。结果TBCB组间质性肺炎、肺泡蛋白沉着症、血管内大B细胞淋巴瘤以及肺淋巴管平滑肌瘤病检出率分别为86.08%、2.53%、2.37%、7.59%,和胸腔镜组的83.54%、1.27%、2.53%、6.33%比较,差异无统计学意义(均P>0.05)。TBCB组术后并发症总发生率为7.59%,明显低于胸腔镜组的26.58%,差异有统计学意义(P<0.05)。TBCB组医疗费用少于胸腔镜组,且术后住院时长短于胸腔镜组,差异有统计学意义(均P<0.05)。TBCB组满意度高于胸腔镜组,差异有统计学意义(P<0.05)。结论TBCB检测技术对肺部弥散性疾病患者病理诊断的作用价值较高,更值得临床推广普及。

Objective To study the role of transbronchoscopic frozen lung biopsy(TBCB)in the pathological diagnosis of pulmonary diffuse diseases.Methods A total of 79 patients with pulmonary diffuse disease admitted to the hospital from February 2017 to February 2020 were included in the study.TBCB test and video-assisted pulmonary biopsy were performed on all subjects.The effects of the two methods on the detection of pulmonary diffuse disease,postoperative complications,medical expenses,postoperative hospital stay,and patient satisfaction were compared.Results The detection rates of interstitial pneumonia,alveolar proteinosis,intravascular large b-cell lymphoma,and pulmonary lymphangitic leiomyomatosis in the TBCB group were 86.08%,2.53%,2.37%,and 7.59%,respectively,compared with 83.54%,1.27%,2.53%,and 6.33%in the video-assisted thoracoscopy group,the differences were not statistically significant(all P>0.05).The total incidence of postoperative complications in the TBCB group was 7.59%,which was significantly lower than thoracoscopic group of 26.58%,the difference was statistically significant(P<0.05).The medical expenses of the TBCB group were lower than thoracoscope group,and the length of hospitalization after surgery was longer than thoracoscope group,the differences were statistically significant(all P<0.05).The satisfaction of THE TBCB group was higher than that of the thoracoscope group,the difference was statistically significant(P<0.05).Conclusion TBCB detection technology has a high value in the pathological diagnosis of patients with diffuse pulmonary diseases,and is more worthy of clinical popularization.