高龄急性缺血性脑卒中复发的危险因素及其防治

Risk factors for recurrence of acute ischemic stroke in advanced aged patients and its prevention and treatment strategies

目的:探讨高龄急性缺血性脑卒中复发的危险因素及其防治策略。方法:选择在我院治疗的128例高龄急性缺血性脑卒中患者为研究对象,按一年内有无复发分为复发组(46例)和无复发组(82例),采用单因素及多因素Logistic回归分析筛选其独立危险因素。结果:单因素分析结果显示:复发组患者的年龄≥80岁、吸烟、糖尿病、房颤、入院美国国立卫生研究院卒中量表(NIHSS)评分>4分、服药依从性差的比例显著高于无复发组(P<0.05或<0.01);多因素Logistic回归分析结果显示:年龄≥80岁、糖尿病、房颤、入院NIHSS评分>4分、服药依从性差均是高龄急性缺血性脑卒中复发的独立危险因素(OR=2.494~5.025,P<0.05或<0.01)。结论:年龄≥80岁、合并有糖尿病及心房颤动、入院NIHSS评分>4分,且服药依从性差的高龄急性缺血性脑卒中患者易复发,可根据上述危险因素采取有针对性的防治措施。

Objective:To explore risk factors for recurrence of acute ischemic stroke(AIS)in advanced aged patients and its prevention and treatment strategies.Methods:According to recurrence within one year or not,a total of 128 advanced aged patients with AIS treated in our hospital were divided into recurrence group(n=46)and no recurrence group(n=82).Single-and multi-factor Logistic regression were used to screen its independent risk factors.Results:Single factor analysis indicated that compared with no recurrence group,there were significant rise in percentages of age≥80 years,smoking,diabetes mellitus,atrial fibrillation,United States National Institutes of Health Stroke Score(NIHSS)score>4 scores at hospitalization and poor administration compliance in recurrence group,P<0.05 or<0.01;multi-factor Logistic regression analysis indicated that age≥80 years,diabetes mellitus,atrial fibrillation,NIHSS score>4 scores at hospitalization and poor administration compliance were independent risk factors for recurrence of AIS in advanced aged patients(OR=2.494~5.025,P<0.05 or<0.01).Conclusion:Advanced aged AIS patients with age≥80 years,diabetes mellitus,atrial fibrillation,NIHSS score>4 scores at hospitalization and poor administration compliance are easy to recur,targeted preventive and therapentic measures can be performed accorcling-to above risk factors.