腹腔镜胆囊切除术治疗急性结石性胆囊炎对胃肠功能CRP水平的影响

Effect of laparoscopic cholecystectomy on gastrointestinal function and CRP level of acute calculous cholecystitis

目的探究腹腔镜胆囊切除术对急性结石性胆囊炎患者的胃肠功能、炎性因子的影响。方法选取大冶市人民医院2019年2月—2020年3月收治的急性结石性胆囊炎112例为研究对象,依据双盲法随机分成腹腔组与传统组,其中传统组(n=56)行开腹手术治疗,腹腔组(n=56)行腹腔镜胆囊切除术治疗。观察2组患者的胃肠道功能、并发症发生率及其治疗前后白介素8(IL-8)、C反应蛋白(CRP)水平。结果腹腔组患者的正常进食时间、排气时间为、肠鸣音恢复时间、CRP、IL-8显著低于传统组;腹腔组的并发症总发生率为5.36%,显著低于传统组的25.00%,差异显著(P<0.05)。结论急性结石性胆囊炎经腹腔镜胆囊切除术治疗后,患者的胃肠道功能恢复良好,炎症反应更轻,具有较高的安全性。

Objective To investigate the effect of laparoscopic cholecystectomy on gastrointestinal function and inflammatory factors in patients with acute calculous cholecystitis.Methods The acute calculous cholecystitis(n=112)admitted in our hospital from february 2019 to march 2020 was taken as the object of study.according to the double-blind method,the selected patients were divided into abdominal group and traditional group,in which the traditional group(n=56)underwent open surgery and the abdominal group(n=56)underwent laparoscopic cholecystectomy.The gastrointestinal function,complication rate and interleukin 8(IL-8)and C-reactive protein(CRP)were observed before and after treatment.Results The normal feeding time,exhaust time,recovery time and CRP、IL-8 of bowel sounds were significantly lower in the abdominal group than in the traditional group.and the total incidence of complications in the abdominal group was 5.36%,which was significantly lower than that in the traditional group of 25.00%(P<0.05).Conclusion After the treatment of acute calculous cholecystitis by laparoscopic cholecystectomy,the gastrointestinal function of the patients recovered well,the anti-inflammatory effect was strong,and the safety was better.