全球3D生物打印技术研究态势分析

Research Situation Analysis of Global 3D Bioprinting Technology

本文以Web of Science核心合集数据库为统计源,对该数据库收录的3D生物打印技术的文章进行文献计量学分析,利用德温特数据分析软件(Derwent Data Analyzer,DDA)和VOSviewer可视化软件,对全球3D生物打印技术领域发展态势进行分析。Web of Science核心合集数据库收录3D生物打印技术研究领域文献15736篇,发文量总体呈逐年上升的趋势,研究热点集中在支架和组织工程方向。2015年以来,全球3D生物打印技术方面的发文量有显著增长。美国发文量最多,中国排名第二;发文量最多的机构是美国的加州大学系统,中国发文量最多的机构是上海交通大学;发文量最多的作者是澳大利亚昆士兰科技大学的Hutmacher Dietmar W。基于众多科研实力强劲的高校和顶尖人才,美国处于全球3D生物打印研究合作网络的中心,在全球研究合作网络中占据重要地位。中国3D生物打印技术的研究发展速度快,整体处于国际领先水平,但是在学术影响力方面与国际顶尖水平相比尚有差距,在立体光刻、计算机辅助设计等方面的研究还有待加强。因此,我国还需加强重大基础和前沿科学研究,不断深化国际交流合作,引育一批国际顶尖科技人才,促进我国3D生物打印技术和产业的发展。

This article uses the Web of Science core collection database as the statistical source,carries on the bibliometric analysis of the 3 D bioprinting technology articles included in the database,and uses Derwent Data Analyzer(DDA)and VOS viewer visualization software to compare the development trend of global 3 D bioprinting technology.The Web of Science core collection database contains 15736 articles in the research field of 3 D bioprinting technology,and the amount of publications is generally increasing year by year.Research hotspots are concentrated in the direction of scaffolds and tissue engineering.Since 2015,the number of articles published on 3 D bioprinting technology has increased significantly.The United States has the largest number of papers,and China ranks second.The institutions with the largest number of published papers are the University of California System in the United States,Shanghai Jiaotong University as the most prolific institution in China,and Hutmacher Dietmar W of the Queensland University of Technology is the most prolific author.With many universities and top talents with strong scientific research strength,the United States is at the center of the global 3 D bioprinting research cooperation network and occupies an important position in the global research cooperation network.The research and development of 3 D bioprinting technology in China is fast,and occupies the international leading level.However,there is still a gap in terms of China’s academic influence compared to the international top level.Research in stereolithography,computer-aided design,etc.,needs to be strengthened.Therefore,China still needs to strengthen major basic and cutting-edge scientific research,continuously deepen international exchanges and cooperation,attract a number of international top scientific and technological talents,and promote the development of 3 D bioprinting technology and industry.