摘要
Since 1981,worldwide leprosy prevalence has declined sharply due to the implementation of multidrug therapy(MDT)conducted by the World Health Organization(WHO).The national prevalence of leprosy finally decreased to 0.05 per 10,000 population in 1998,which meant the WHO threshold of leprosy elimination(below 1 per 10,000 population)was reached in China through a wellorganized control network and through the implementation of MDT(1).However,the number of newly registered leprosy cases each year,the grade 2 disability(G2D)rate,as well as the rate of fatal adverse drug reactions(ADR)had not significantly changed since 1998(2–3),so leprosy is still seen as a public health problem in China.In addition,dermatological clinics rather than leprosy control stations became the main source for leprosy case finding at every level.Delayed diagnosis was common due to a general lack of awareness and adequately precise techniques among dermatologists to detect Mycobacterium leprae(M.leprae)that results in leprosy.