宫颈电刀锥切术对宫颈上皮内瘤变Ⅲ级患者手术相关指标及复发率的影响

Effect of Cervical Electrosurgical Knife Conization on Operation-related Indexes and Recurrence Rate of Patients with Cervical Intraepithelial Neoplasia Grade Ⅲ

目的:探究宫颈电刀锥切术对宫颈上皮内瘤变(CIN)Ⅲ级患者手术相关指标及复发率的影响。方法:回顾性分析2017年1月~2021年4月某院收治的92例CINⅢ级患者资料,依据手术方法的不同分为冷刀组(43例)和电刀组(49例),冷刀组采用冷刀宫颈锥切术,电刀组行宫颈电刀锥切术,术后随访3个月。对比两组围术期指标、并发症发生率及复发率。结果:电刀组手术时间为(24.34±7.93)min,住院时间为(2.04±0.53)d,均短于冷刀组的(29.86±6.84)min、(4.11±0.62)d,电刀组术中出血量为(14.50±3.74)ml,少于冷刀组的(26.08±8.97)ml,差异有统计学意义(P<0.05);电刀组术后并发症发生率为6.12%,低于冷刀组的20.93%,差异有统计学意义(P<0.05);电刀组术后复发率为2.04%,冷刀组术后复发率为9.30%,两组比较差异无统计学意义(P>0.05)。结论:冷刀锥切术与宫颈电刀锥切术在CINⅢ治疗中均可获得良好效果,可减少病灶残留,术后复发率低,但宫颈电刀锥切术后并发症更少,利于患者术后恢复。

Objective:To explore the effect of cervical electrosurgical knife conization on operation-related indexes and recurrence rate of patients with cervical intraepithelial neoplasia gradeⅢ.Methods:The data of 92 patients with CIN grade III admitted to a hospital from January 2017 to April 2021 were retrospectively analyzed,and all patients were divided into cold knife group(43 cases)and electric knife group(49 cases)according to different surgical methods.Cold knife group underwent cold knife cervical conization,and electric knife group underwent cervical electrosurgical knife conization.All patients were followeded up for 3 months.The perioperative indicators,incidence of complications and recurrence rate were compared between the two groups.Results:The operation time of the electric knife group was(24.34±7.93)min,and the hospital stay was(2.04±0.53)d,which were shorter than those of the cold knife group[(29.86±6.84)min and(4.11±0.62)d],the intraoperative blood loss was(14.50±3.74)ml,less than(26.08±8.97)ml in the cold knife group,and the difference was statistically significant(P<0.05).The incidence of postoperative complications of the electric knife group was 6.12%,which was lower than that in the cold knife group(20.93%),the difference was statistically significant(P<0.05).The postoperative recurrence rate in the electric knife group was 2.04%,and the postoperative recurrence rate in the cold knife group was 9.30%.There was no statistically significant difference between the two groups(P>0.05).Conclusion:Both cold knife conization and cervical electrosurgical knife conization can achieve good results in the treatment of CINⅢ,which can reduce residual lesions and have a low postoperative recurrence rate.However,there are fewer complications after cervical electrosurgical knife conization,which is beneficial to patients recovery after operation.