芩柏通络散联合硒温泉治疗糖尿病周围神经病的RCT临床研究

RCT Clinical Research on Qinbai Tongluo Powder Combined with Selenium Hot Spring in the Treatment of Diabetic Peripheral Neuropathy

目的观察自拟方芩柏通络散联合硒温泉熏洗治疗糖尿病周围神经病(Diabetic peripheral neuropathy,DPN)的临床疗效。方法选取宜春市中医院中医内科收治的湿热血瘀型DPN患者80例,按照RCT的临床试验方案随机分为对照组、治疗组,每组40例。治疗组给予芩柏通络散联合硒温泉熏洗患处,并随证加减;对照组给予普通温水熏洗患处,疗程均为2周。结果对照组总有效率为57.5%(23/40),治疗组为95.0%(38/40),治疗组效果优于对照组,差异有统计学意义(P<0.05)。结论硒温泉联合自拟方芩柏通络散熏洗治疗DPN疗效好,且安全性高,值得推广。

Objective To observe the clinical effect of the Qinbai Tongluo powder combined with selenium hot spring in treating acute diabetic peripheral neuropathy(DPN).Methods 80 patients with DPN disease of dampness-heat and blood stasis type were randomly divided into control group and treatment group,with 40 cases in each group.The treatment group patients accepted fumigation and washing therapy by using Qinbai Tongluo powder combined with selenium hot spring.The control group patients accepted fumigation and washing therapy by using ordinary warm water.The clinical efficacy was evaluated after 2 week.Results The total effective rate of the control group was 57.5%(23/40),and that of the treatment group was 95.0%(38/40).The effect of the treatment group was better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Qinbai Tongluo powder combined with selenium hot spring in treating DPN of dampness-heat and blood stasis type has good efficacy and high safety,which is worth popularizing.