卵巢早衰的中西医病因分析及治疗现状研究

Etiology Analysis and Treatment Status of Premature Ovarian Failure in Traditional Chinese Medicine and Western Medicine

卵巢早衰(Premature ovarian failure,POF)是指女性在40岁以前出现闭经、不孕、雌性激素分泌下降和促性腺激素增高等症状的一种疾病,严重危害女性健康,容易产生各种生殖内分泌、甚至全身性问题。其西医发病机制尚不清楚,可能与遗传、免疫、酶缺乏、医源性、环素、心理等因素有关;中医则认为病因与肾、肝、脾相关,主要分为肾虚肝郁证、肝肾阴虚证、脾肾阳虚证等。西医治疗方法包括激素替代疗法、免疫治疗、促排卵等,中医以中药口服、针灸等疗法为主。文章通过文献研究,对卵巢早衰的中西医病因病理机制和治疗现状进行探讨。

Premature ovarian failure(POF)refers to female before the age of 40 appears symptoms of amenorrhea,infertility,estrogen secretion declined and gonadotropin increased.It is a disease that may prone to a variety of reproductive endocrine,and even systemic problems,that brings serious harm to health.For western medicine,the pathogenesis of is not clear,including genetic,immune,enzyme deficiency,iatrogenic,cyclin,and psychological factors.And for Chinese medicine,the etiology is considered to be related to the dysfunction of kidney,liver and spleen,mainly including kidney deficiency and liver stagnation syndrome,liver and kidney yin deficiency syndrome,spleen and kidney yang deficiency syndrome.In terms of treatment,western medicine adopts hormone replacement therapy,immunotherapy and ovulation induction,while Chinese medicine mainly adopts oral Chinese medicine and acupuncture.Through literature research,this paper studies and discusses the etiology,pathology mechanism and treatment status of premature ovarian failure in Chinese and western medicine.