抗幽门螺杆菌治疗对幽门螺杆菌感染的2型糖尿病患者血糖、炎性因子和血脂的影响

Effect of anti-helicobacter pylori therapy on blood glucose,inflammatory factors and blood lipids in helicobacter pylori infected patients with type 2 diabetes mellitus

目的探讨抗幽门螺杆菌治疗对糖尿病合并幽门螺杆菌患者的血糖、炎性因子和血脂的影响。方法2019年5月至2021年4月,以在牡丹江医学院附属红旗医院治疗的糖尿病合并幽门螺杆菌患者150例为治疗对象。采取随机数字表法将患者分为对照组和观察组,每组各75例。对照组行控制血糖治疗,观察组增加抗幽门螺杆菌治疗。治疗后,比较两组患者的血糖、炎性因子和血脂的检测结果。结果治疗后,观察组空腹血糖和餐后2 h血糖检测结果均低于对照组,白细胞介素-6(IL-6)和白细胞介素-8(IL-8)检测结果低于对照组,胆固醇、三酰甘油和低密度脂蛋白低于对照组,高密度脂蛋白高于对照组,以上比较差异均有统计学意义(P<0.05)。结论抗幽门螺杆菌治疗,可进一步改善患者的血糖、炎性因子和血脂等检测结果。

Objective To explore the effect of helicobacter pylori(Hp)treatment on blood glucose,inflammatory factors and blood lipids in patients with diabetes mellitus complicated with Hp infection.Methods A total of 150 patients with diabetes mellitus complicated with Hp infection treated in Hongqi Hospital Affiliated to Mudanjiang Medical University from May 2019 to April 2021 were selected as research objects.Patients were divided into the control group and the observation group based on the random number table method,with 75 patients in each group.The control group was treated with blood glucose control.In th e observation group,anti-Hp treatment was added.After treatment,the blood glucose,inflammatory factors and blood lipids were compared between the two groups.Results After treatment,the levels of fasting blood glucose,2-hour postprandial blood glucose,interleukin-6(IL-6),interleukin-8(IL-8),cholesterol,triglyceride and low-density lipoprotein in the observation group were lower than those in the control group,and high-density lipoprotein was higher than that in the control group,with statistically significant differences(P<0.05).Conclusion Anti-Hp treatment can further improve the detection results of blood sugar,inflammatory factors and blood lipids.