摘要
获得性血友病A(acquired hemophilia A,AHA)死亡率为15%~42%,约50%左右的AHA为特发性,而另外50%与一些基础疾病有关,如系统性红斑狼疮、肿瘤、药物过敏、皮肤病(如银屑病,大疱性类天疱疮)等。本文报道一例大疱性类天疱疮合并获得性血友病,采用泼尼松、人凝血酶原复合物联合环孢素治疗后取得了显著疗效。
The mortality rate of acquired hemophilia A(AHA)is 15%-42%,about 50%of AHA is idiopathic,and the other 50%is related to some underlying diseases,such as systemic lupus erythematosus,tumor,drug allergy,skin diseases(such as psoriasis,bullous pemphigoid)and so on.Herein,we report a patient with bullous pemphigoid complicated with AHA,who achieved significant efficacy after comprehensive treatment of oral prednisone and human prothrombin complex,cyclosporine.
作者
车炫霖
粟娟
陈明亮
CHE Xuanlin;SU Juan;CHEN Mingliang(Department of Dermatology,Xiangya Hospital,Central South University,Changsha 410008,China;Hunan Key Laboratory of Skin Cancer and Psoriasis,Central South University,Changsha 410008,China;Hunan Engineering Research Center of Skin Health and Disease,Central South University,Changsha 410008,China;National Clinical Research Center for Geriatric Disorders(Xiangya Hospital),Changsha 410008,China)
出处
《中国麻风皮肤病杂志》
2022年第2期110-111,共2页
China Journal of Leprosy and Skin Diseases
