中枢性卒中后疼痛治疗药物的研究进展

Research progress of drug treatment of central post-stroke pain

中枢性卒中后疼痛是一种脑血管意外发生后的神经病理性疼痛综合征,临床表现为肌肉骨骼疼痛、感觉异常或其他感觉障碍等,并且疼痛部位与脑血管病变损伤的大脑区域相对应。目前临床上对中枢性卒中后疼痛的治疗包括药物、非药物治疗。中枢性卒中后疼痛的治疗药物主要包括抗抑郁药、抗癫痫药、阿片类药物和麻醉药等。就治疗中枢性卒中后疼痛的药物进行综述。

Central post-stroke pain is a neuropathic pain syndrome after cerebrovascular accident. Clinical manifestations are muscle,bone pain, sensory abnormalities or other sensory disorders, and the pain site corresponds to the brain area of cerebrovascular disease.At present, the clinical treatment of central post-stroke pain includes drug and non-drug treatment. The treatment drugs for CPSP mainly include antidepressants, antiepileptics, opioids and anesthetics, etc. This article reviews progress in drug therapy for central post-stroke pain.