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用OCT探究艾灸后皮肤组织的光衰减变化 被引量:1

Using OCT to explore the light attenuation changes of skin tissue after moxibustion
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摘要 使用OCT初步探究了艾灸对经络上不同穴位表皮微循环的影响。对每位健康志愿者先后进行3次大陵穴艾灸实验,共得到30组实验数据。每组对4个观测点进行10次测量,共获得1200次实验数据。基于OCT信号的成像特性与组织光学中的光学特性参数,对穴位处深度为0.4~1.0mm的后向散射信号区间内进行拟合,获得了穴位皮肤的光衰减系数。结果显示,与自然状态下的皮肤光衰减系数相比艾灸后30min内穴位皮肤光衰减系数升高约40%,艾灸点所在经络上的其他穴位后向散射信号强度明显降低。而在临近经络的非穴位对照点和其他经络上的对照点处并没有观察到这一现象。表明了,利用OCT可以观测到艾灸对穴位皮肤微循环的影响可以通过经络这一通道进行传递至其它穴位,这种现象具有一定的临床意义,也进一步扩展了传统OCT的运用范围。 The OCT is used to preliminary explore the effect of moxibustion on epidermal microcirculation at different points on the meridian.Three moxibustion experiments were carried out for each healthy volunteer,and a total of 30 experimental data were obtained.Each group performed 10 measurements on four observation points,and a total of 1200 data were obtained.Based on the imaging characteristics of OCT signals and the optical characteristic parameters in tissue optics,the backscattered signal interval at the acupoint depth of 0.4~1.0 mm is fitted to obtain the light attenuation coefficient of the acupoint skin.The results show that compared with the skin light attenuation coefficient in the natural state,the skin light attenuation coefficient of acupuncture points increases by about 40% within 30 minutes after moxibustion,and the backscattered signal intensity of other acupoints on the meridian point where the moxibustion point was located is significantly reduced.This phenomenon is not observed at non-acupoint control points near the meridians and at other control points on the meridians.The results show that the effect of moxibustion on acupoint skin microcirculation can be transmitted to other acupuncture points through the channels of meridians using OCT.This phenomenon has certain clinical significance and further extends the scope of application of traditional OCT.
作者 陈明惠 高乃珺 王帆 张晨曦 郑刚 CHEN Minghui;GAO Naijun;WANG Fan;ZHANG Chenxi;ZHENG Gang(Institute of Biomedical Optics&Optometry,Shanghai Interventional Medical Device Engineering Technology Research Center,University of Shanghai for Science and Technology,Shanghai 200093,China)
出处 《光学技术》 CAS CSCD 北大核心 2021年第6期672-678,共7页 Optical Technique
基金 上海市自然科学基金(13ZR1457900) 上海市科委产学研医项目(15DZ1940400)。
关键词 光学相干层析 艾灸 微循环 衰减系数 optical coherence tomography moxibustion microcirculation attenuation coefficient
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