1990—2017年内蒙古自治区心血管疾病负担研究

The growing burden of cardiovascular diseases in Inner Mongolia Autonomous Region from 1990to 2017

目的分析内蒙古自治区1990—2017年心血管病的疾病负担及变化情况,为心血管疾病防控提供依据。方法本研究数据来源于2017年全球疾病负担(the 2017 global burden of disease study, GBD2017)中国分省研究中内蒙古自治区的数据。计算死亡率、患病率、早死损失寿命年率(years of life lost, YLL率)、伤残损失寿命年率(years lived with disability, YLD率)、伤残调整寿命年(disability adjusted of life years, DALYs)和DALY率等。结果 1990—2017年,内蒙古自治区心血管病死亡率从222.98/10万上升至347.14/10万,升幅55.68%,男性、女性分别上升57.37%、53.44%;YLL率从5 584.45/10万上升至6 643.30/10万,升幅18.96%,男性、女性分别上升29.93%、4.01%;患病率从4 142.47/10万上升至8 457.09/10万,升幅104.16%,男性、女性分别上升97.19%、111.54%;YLD率从397.01/10万上升至858.90/10万,升幅116.34%,男性、女性分别上升117.04%、115.64%;DALY率升幅25.42%,男性、女性分别上升35.02%、12.61%。在各类心血管疾病中,DALY率最高的为卒中(3 553.43/10万),其次为缺血性心脏病(3 272.56/10万),但2015年后缺血性心脏病YLL率超越卒中,成为首位。此外,心房颤动与扑动和外周动脉疾病DALY率增幅最大(168.87%、132.82%)。结论 1990—2017年,内蒙古自治区心血管疾病负担整体呈增长趋势,有性别差异,卒中和缺血性心脏病疾病负担最重,心房颤动与扑动和外周动脉疾病疾病负担上升最明显。

Objective To understand the trend of cardiovascular disease(CVD) burden in Inner Mongolia during 1990 and 2017, and to provide the evidence for the prevention and control of cardiovascular disease. Methods Data were retrieved from Global Burden of Disease Study 2017(GBD 2017).Mortality, morbidity, years of life lost(YLLs) rate, years lived with disability( YLDs) rate and disability adjusted life years(DALY) were metrics used to measure CVD burden. Results In inner Mongolia Autonomous Region, from 1990 to 2017, the mortality and morbidity rates increased by 55.68% and 104.16%(57.37% and 97.19% in men;53.44% and 111.54% in women), from 222.98/100 000 to 347.14/100 000 and from 4 142.47/100 000 to 8 457.09/100 000, respectively.The YLL rate increased from 5 584.45/100 000 to 6 643.30/100 000, with 18.96% increase(29.93% in male and 4.01% in female).The YLD rate increased by 116.34%, from 397.01/100 000 in 1990 to 858.90/100 000 in 2017, with 117.04% increase in male and 115.64% in female.DALY rate increased by 25.42%(35.02% in men and 12.61% in women).Among all types of cardiovascular disease,stroke was the leading cause of CVD DALYs with the highest rate of 3 553.43/100 000,followed by ischemic heart disease with DALY rate of 3 272.56/100 000.However,after 2015,the YLL rate of ischemic heart disease surpassed that of stroke.In addition,DALY rate of atrial fibrillation and flutter and peripheral artery disease increased significantly(168.87%,132.82%). Conclusions From 1990 to 2017,the burden of cardiovascular disease in Inner Mongolia showed an upward trend,with significant gender difference.Stroke and ischemic heart disease contributed the most on disease burden compared with other cardiovascular diseases,while the burden of atrial fibrillation and flutter and peripheral artery disease grew rapidly.