不同认知偏向训练对男性酒依赖患者戒酒治疗后的注意偏向及复饮率影响

Effects of different cognitive bias modification training on attention bias and relapse rate in male alcohol-dependent patients

目的:探讨不同认知偏向训练(CBM)对男性酒依赖(AD)患者戒酒治疗后的注意偏向与复饮率影响。方法:80例戒酒治疗的男性AD患者按住院号随机分为两组,常规训练(RT)组接受常规CBM,信息回避(IA)组接受酒相关信息回避CBM。训练前后采用中文情绪词Stroop任务测验对两组AD患者进行注意偏向评估,与40名健康对照者(HC组)比较;患者出院2、4、6个月时电话随访其复饮情况。结果:训练前,各组Stroop任务中负性词、中性词与线索词的反应时比较及负性词、中性词错误数比较差异有统计学意义;RT组及IA组的负性词、中性词与线索词的反应时及负性词、中性词的错误数明显大于HC组(P均<0.01)。训练后,RT组及IA组负性词、中性词及线索词的反应时明显缩短(P均<0.01);RT组负性词、中性词与线索词的错误数及IA组的负性词、中性词的错误数与训练前比较差异无统计学意义;IA组线索词的错误数明显大于治疗前(P<0.01)及RT组(P<0.05)。出院后2及4个月时,RT组复饮率明显低于IA组(P均<0.05),6个月时两组间差异无统计学意义。结论:常规CBM对男性AD患者注意偏向的修正及短期减少复饮率略好于信息回避CBM。

Objective:To explore the effects of different cognitive bias modification training(CBM)on attention bias and relapse rate in male alcohol-dependent(AD)patients.Method:A total of 80 male AD patients were randomly divided into two groups according to the hospital number.The routine training(RT)group received conventional CBM,the information avoidance(IA)group received alcohol-related information avoidance CBM.The attentional bias of the two groups of AD patients was assessed by Chinese emotional word Stroop task test before and after the training,the results were compared with 40 healthy controls(HC group).The patients were followed up by telephone 2,4 and 6 months after discharge.Results:①The reaction time of neutral,negative and alcohol-related words and the error number in Chinese emotional Stroop task among three groups were significantly different,The reaction time of neutral-,negative-and alcohol-words and the error number in Chinese Emotional Stroop Task of the RT group and IA at baseline were larger than those of HC group(all P<0.01);The error number of neutral、negative-related words in Chinese Emotional Stroop Task of the RT group and IA group were larger than that of HC group(all P<0.01).After training,the reaction time of neutral,negative and alcohol-related words in the RT group and IA group was shorter than that before treatment.There were no significant differences in the error number of negative-,neutra-,alcohol-related words of the RT group and the error number of negative-,neutral-related words of IA group before and after training.The error number of alcohol-words in the IA group was more than that before training(P<0.01)and the RT group after training(P<0.05).The relapse rate in RT group was lower than that in IA group at 2 and 4 months after hospital discharge,but there was no significant difference between the two groups after 6 months.Conclusion:Conventional CBM is slightly better than information avoidance CBM in the correction of attentional bias and short-term reduction in relapse rate in male AD patients.