关于ICC重新定义、分类和命名的建议

Suggestions on definition,classification and nomenclature of intrahepatic cholangiocarcinoma

目前ICC(intrahepatic cholangiocarcinoma)的定义、分类和中文命名存在争议。ICC属于肝癌还是胆管癌, 归属不清晰, 而且"肝内胆管癌"与"胆管细胞癌"两个名称在临床中无区别地同时应用, 给实际工作带来混乱。笔者依据国内外权威文献, 对ICC的归属、分类和中文命名、以及胆管癌分类提出新建议, 指出cholangiocarcinoma的中文翻译应为"胆管上皮癌(胆管细胞癌)"而不是"胆管癌";将肿块型ICC归属于"原发性肝癌", 命名为"肝胆管细胞癌";而管周浸润型ICC和管内生长型ICC仍归属为"胆管癌", 命名为"肝门周胆管癌", 从而将"胆管癌"分类为肝门周胆管癌、肝门部胆管癌和远端胆管癌。

Currently,the definition,classification and Chinese nomenclature of intrahepatic cholangiocarcinoma(ICC)are controversial.Whether ICC belongs to liver cancer or carcinoma of bile duct is debatable,and the two terms"intrahepatic cholangiocarcinoma"and"cholangiocellular carcinoma"are simultaneously used without distinction,bringing great confusions to clinical practice.Based on authoritative literatures at home and abroad,the authors give suggestions on the definition,classification and Chinese nomenclature of ICC,as well as the classification of carcinoma of bile duct,which recommend that the Chinese translation of"cholangiocarcinoma"should be"epithelial carcinoma of bile duct(cholangiocellular carcinoma)",the mass-forming type ICC should be classified as primary liver cancer,naming as"intrahepatic cholangiocarcinoma"and the periductal-infiltrating type and intraductal-growing type ICCs still be classified as carcinoma of bile duct,naming as"perihilar cholangiocarcinoma".The authors recommend to classify carcinoma of bile duct into:perihilar cholangiocarcinoma,hilar cholangiocarcinoma,and distal cholangiocarcinoma.