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岛状眶下神经血管蒂唇腺移植术治疗重度干眼一例

Insular infraorbital neurovascular pedicle labial salivary gland transplantation for severe dry eye:a case report
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摘要 1例52岁男性患者因双眼干涩5年, 就诊于首都医科大学附属北京同仁医院北京同仁眼科中心。既往因感冒药物过敏诊断为Steven-Johnson综合征。眼部检查双眼泪液分泌试验结果为0 mm, 泪膜破裂时间为0 s, 角膜荧光素染色可见角膜上皮糜烂, 部分融合。临床诊断为双眼干眼(重度);Steven-Johnson综合征。常规人工泪液、抗炎滴眼液及泪小点栓塞治疗无明显效果后, 行具有创新性的岛状眶下神经血管蒂唇腺移植术。术后随访1年, 患者术眼干眼症状及体征均明显改善, 手术效果满意。(中华眼科杂志, 2021, 57:946-948) A 52-year-old male presented to Beijing Tongren Hospital with a 5-year history of bilateral dry eyes.He had been diagnosed with Steven-Johnson syndrome due to allergy to cold medication.On examination,the Schirmer I test value was 0 mm,the tear break-up time was 0 s,and corneal fluorescein staining showed corneal epithelial erosion with partial fusion in both eyes.The clinical diagnosis was dry eyes(severe)and Steven-Johnson syndrome.No significant effect was observed after use of artificial tears and anti-inflammatory eye drops and tear punctal embolization.Then an insular infraorbital neurovascular pedicle labial salivary gland transplantation was performed in the right eye.During the 1-year postoperative follow-up,the symptoms and signs were significantly improved in the operated eye,and the surgical results were satisfactory.(Chin J Ophthalmol,2021,57:946-948)
作者 杨珂 陈晓红 周晶 王滢珲 朴颖实 李眉 程昀 接英 Yang Ke;Chen Xiaohong;Zhou Jing;Wang Yinghui;Piao Yingshi;Li Mei;Cheng Yun;Jie Ying(Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Institute of Ophthalmology,Beijing Key Laboratory of Ophthalmology&Visual Sciences,Beijing 100730,China;Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Department of Pathology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Department of Nuclear Medicine,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Department of Ultrasound Diagnosis,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处 《中华眼科杂志》 CAS CSCD 北大核心 2021年第12期946-948,共3页 Chinese Journal of Ophthalmology
关键词 干眼综合征 涎腺 移植 Dry eye syndromes Salivary glands Transplantation
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